A PDMS-based microneedle array electrode for long-term ECG recording
A PDMS-based microneedle array electrode for long-term ECG recording
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基于PDMS的微针阵列电极用于长期心电图记录
DOI：
10.1007/s10544-022-00626-y
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发表时间：
2022-08
影响因子：
2.8
通讯作者：
Wendong Zhang
中科院分区：
文献类型：
--
作者：
Renxin Wang;Jianxin Bai;Xiaohang Zhu;Zhaodong Li;Lixia Cheng;Guojun Zhang;Wendong Zhang
为了获得高质量的心电信号，传统的银/氯化银湿电极结合导电凝胶可以在短期内有效降低电极-皮肤界面阻抗(EII)。然而，它们灵活性差、不稳定的弱点已经不能满足智能可穿戴设备的长期监控要求。由于没有导电胶的柔性干燥电极，是解决导电胶干燥的关键问题的一个很好的选择。因此，我们开发了一种基于聚二甲基硅氧烷(PDMS)衬底的柔性微针阵列电极(FMAE)，通过穿透皮肤角质层(SC)的方式获得可靠的生物电信号。该制备工艺包括硅模、二次PDMS移形和封装，具有成本低、可重复生产、生物相容性好等优点。然后，通过比较不同电极的性能，阻抗测试结果表明，FMAE的阻抗更小、更稳定，长期和静息/慢跑状态的心电测试也验证了FMAE能够获得持久、稳定和可靠的信号。综上所述，FMAE在长期心电监测中具有广阔的应用前景。
To acquire high-quality electrocardiogram (ECG) signals, traditional Ag/AgCl wet electrodes used together with conductive gel can effectively reduce electrode-skin interface impedance (EII) in a short term. However, their weaknesses of poor flexibility and instability can no longer meet the long-term monitoring requirements of intelligent wearable devices. Owing to the flexible dry electrode without conductive gel, it is a good choice to solve the critical problem on drying-out of conductive gel. Therefore, we develop a flexible microneedle array electrode (FMAE) based on polydimethylsiloxane (PDMS) substrate, which obtains reliable bioelectrical signals by way of penetrating into the stratum corneum (SC) of the skin. The fabrication process, including silicon mold, twice PDMS shape-transferring and encapsulation, has advantages of low cost, repeatable production and good biocompatibility. Afterwards, by comparing the performance with different electrodes, impedance test results indicate that the impedance of FMAE are smaller and more stable, and ECG tests in long term and at resting/jogging states also verify that FMAE can obtain durable, stable and reliable signals. In conclusion, FMAE is promising in long-term ECG monitoring.
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影响因子：
2.7
作者：
Po-Chun Wang;S. Paik;Seong-Hyok Kim;M. Allen
通讯作者：
Po-Chun Wang;S. Paik;Seong-Hyok Kim;M. Allen
影响因子：
2.2
作者：
T. Gardner;G. Briggs
通讯作者：
T. Gardner;G. Briggs
DOI：
10.1111/1523-1747.ep12292018
发表时间：
1971
期刊：
The Journal of investigative dermatology
影响因子：
--
作者：
R. Wildnauer;James W. Bothwell;Alexander B. Douglass
通讯作者：
R. Wildnauer;James W. Bothwell;Alexander B. Douglass
DOI：
10.1002/9783527814633.ch10
发表时间：
2019-11
期刊：
Imaging Technologies and Transdermal Delivery in Skin Disorders
影响因子：
--
作者：
Eman M. Migdadi;R. Donnelly
通讯作者：
Eman M. Migdadi;R. Donnelly
用于心电图记录的皮肤电位变化不敏感干电极
影响因子：
4.6
作者：
Pei, Weihua;Zhang, He;Chen, Hongda
通讯作者：
Chen, Hongda