The impact of pediatric obesity on hospitalized children with lower respiratory tract infections in the United States
The impact of pediatric obesity on hospitalized children with lower respiratory tract infections in the United States
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美国儿童肥胖对下呼吸道感染住院儿童的影响
DOI：
10.1111/crj.12694
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Testa Marcia A.
中科院分区：
文献类型：
--
作者：
Okubo Yusuke;Nochioka Kotaro;Testa Marcia A.
目的肥胖是最常见的公共卫生问题，也是住院儿童临床复杂的危险因素。儿童肥胖对下呼吸道感染的严重程度和发病率的影响尚不清楚。材料与方法我们利用出院记录对2-20岁儿童的支气管炎和肺炎进行了回顾性队列研究。这些数据是从2003年、2006年、2009年和2012年的儿童住院数据库中获得的，并被加权以估计美国的住院人数。采用国际疾病分类第9版临床修订编码(278.0×)对患者是否肥胖进行分类。我们使用多变量Logistic回归模型研究了儿童肥胖与机械通气的使用之间的关系。此外，我们还确定了儿童肥胖、并发血流感染、平均医疗费用和住院时间之间的关系。结果我们估计在2至20岁的儿童中，因肺炎和支气管炎住院的总人数为133602人。肥胖与使用机械通气(调整后OR2.90，95%可信区间2.15-3.90)、合并菌血症或败血症(调整后OR1.58，95%可信区间1.03-2.44)、医疗费用增加(调整后差异383，95%可信区间276-476)、andprolongedlengthofhospitalstay(difference0.32days，95%CI0.23‐0.40days)，afteradjustingforpatientandhospitalcharacteristicsusingmultivariablelogisticregressionmodels.ConclusionsPediatricobesityisanindependentriskfactorforseverityandmorbidityamongpediatricpatientswithlowerrespiratorytractinfections.Thesefindingssuggesttheimportanceofobesitypreventionforpediatricpopulations.显著相关
Objective Obesity is the most common public health problem and is a clinically complicating risk factor among hospitalized children. The impact of pediatric obesity on the severity and morbidity of lower respiratory tract infections remains unclear. Materials and Methods We conducted a retrospective cohort study of bronchitis and pneumonia among children aged 2‐20 years using hospital discharge records. The data were obtained from the Kid's Inpatient Database in 2003, 2006, 2009, and 2012, and were weighted to estimate the number of hospitalizations in the United States. We used the International Classification of Diseases, Ninth Revision, Clinical Modification code (278.0×) to classify whether the patient was obese or not. We investigated the associations between pediatric obesity and use of mechanical ventilation using multivariable logistic regression model. In addition, we ascertained the relationships between pediatric obesity, comorbid blood stream infections, mean healthcare cost, and length of hospital stay. Results We estimated a total of 133 602 hospitalizations with pneumonia and bronchitis among children aged between 2 and 20 years. Obesity was significantly associated with use of mechanical ventilation (adjusted OR 2.90, 95% CI 2.15‐3.90), comorbid bacteremia or septicemia (adjusted OR 1.58, 95% CI 1.03‐2.44), elevated healthcare costs (adjusted difference 383,95%CI 276‐476),andprolongedlengthofhospitalstay(difference0.32days,95%CI0.23‐0.40days),afteradjustingforpatientandhospitalcharacteristicsusingmultivariablelogisticregressionmodels.ConclusionsPediatricobesityisanindependentriskfactorforseverityandmorbidityamongpediatricpatientswithlowerrespiratorytractinfections.Thesefindingssuggesttheimportanceofobesitypreventionforpediatricpopulations.
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影响因子：
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作者：
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影响因子：
9.7
作者：
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