Health effects following exposure to dust from the World Trade Center disaster: An update.

Health effects following exposure to dust from the World Trade Center disaster: An update.
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DOI:
10.1016/j.lfs.2021.120147
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发表时间:
2022-01-15
期刊:
影响因子:
6.1
通讯作者:
Wold LE
Wold LE
中科院分区:
医学2区
文献类型:
--
作者:
Mears MJ;Aslaner DM;Barson CT;Cohen MD;Gorr MW;Wold LE

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世界贸易中心(WTC)大楼倒塌时产生的含有挥发性化学物质和颗粒物(PM)的粉尘、烟雾和烟雾影响了纽约市的数千名市民和急救人员(FR;消防员、医务人员、警察)。幸存的FR和恢复工人越来越容易患上与年龄有关的疾病,他们以前的世贸中心粉尘暴露可能会加速或使情况恶化。本综述概述了已发表的WTC研究有关FR/恢复工人的暴露和年龄相关疾病易感性的因果机制,特别是那些涉及心肺和神经系统。这次审查还强调了最近的调查结果的主要健康影响的心血管,肺,神经系统的健康后遗症从世贸中心粉尘暴露。为了更好地治疗那些在2001年9月11日灾难期间和之后冒着生命危险的人,必须更好地了解世贸中心粉尘暴露对FR的心脏,肺和大脑产生并继续产生的有害机制。
Exposure to dust, smoke, and fumes containing volatile chemicals and particulate matter (PM) from the World Trade Center (WTC) towers’ collapse impacted thousands of citizens and first responders (FR; firefighters, medicals staff, police officers) of New York City. Surviving FR and recovery workers are increasingly prone to age-related diseases that their prior WTC dust exposures might expedite or make worse. This review provides an overview of published WTC studies concerning FR/recovery workers’ exposure and causal mechanisms of age-related disease susceptibility, specifically those involving the cardiopulmonary and neurological systems. This review also highlights the recent findings of the major health effects of cardiovascular, pulmonary, and neurological health sequelae from WTC dust exposure. To better treat those that risked their lives during and after the disaster of September 11, 2001, the deleterious mechanisms that WTC dust exposure exerted and continue to exert on the heart, lungs, and brain of FR must be better understood.
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