Post-Diagnostic Dietary and Lifestyle Factors and Prostate Cancer Recurrence, Progression, and Mortality.

Post-Diagnostic Dietary and Lifestyle Factors and Prostate Cancer Recurrence, Progression, and Mortality.
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DOI:
10.1007/s11912-021-01017-x
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发表时间:
2021-03-10
影响因子:
4.7
通讯作者:
Kenfield SA
Kenfield SA
中科院分区:
医学2区
文献类型:
--
作者:
Langlais CS;Graff RE;Van Blarigan EL;Palmer NR;Washington SL 3rd;Chan JM;Kenfield SA

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这项研究旨在总结1999年至2020年6月期间发表的证据,检查前列腺癌(PC)诊断后的饮食和生活方式与生化复发,PC进展和PC特异性死亡率风险的关系。二级预防是癌症生存率的重要研究领域。越来越多的研究报告了诊断后可改变的行为与PC结局风险之间的关联。关于可改变的生活方式因素和PC的证据仍然有限。在存在多项研究的情况下,结果往往是混合的。然而,研究一致表明,吸烟和全脂牛奶/高脂奶制品的消费与PC复发和死亡的风险较高相关。此外,体力活动和每天半至1杯红葡萄酒与复发风险和PC特异性死亡率降低相关。在未来的研究中,有必要更多地纳入种族/民族多样化的群体,以了解受不良PC结局影响最大的人群中的这些关系。
This study aimed to summarize evidence published between 1999 and June 2020 examining diet and lifestyle after prostate cancer (PC) diagnosis in relation to risk of biochemical recurrence, PC progression, and PC-specific mortality. Secondary prevention is an important research area in cancer survivorship. A growing number of studies have reported associations between post-diagnostic modifiable behaviors and risk of PC outcomes. Evidence on modifiable lifestyle factors and PC remains limited. Where multiple studies exist, findings are often mixed. However, studies consistently suggest that smoking and consumption of whole milk/high-fat dairy are associated with higher risk of PC recurrence and mortality. In addition, physical activity and ½ to 1 glass of red wine/day have been associated with lower risk of recurrence and PC-specific mortality. Greater inclusion of racially/ethnically diverse groups in future research is necessary to understand these relationships in populations most impacted by adverse PC outcomes.
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