The Combined Use of Negative-Pressure Wound Therapy and Dermal Substitutes for Tissue Repair and Regeneration.
The Combined Use of Negative-Pressure Wound Therapy and Dermal Substitutes for Tissue Repair and Regeneration.
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结合使用负压伤口疗法和真皮替代品进行组织修复和再生。
DOI：
10.1155/2020/8824737
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发表时间：
2020
影响因子：
--
通讯作者：
Wang X
中科院分区：
文献类型：
--
作者：
Zhang L;Weng T;Wu P;Li Q;Han C;Wang X
在临床实践中，由于各种急慢性疾病引起的皮肤缺损是经常发生的。这些伤口的标准治疗方法是自体移植，这通常会导致并发症，如疤痕形成和供体部位的新伤口。真皮替代物的出现为创面修复提供了一种新的方法，而真皮替代物的快速血管生成对移植的顺利进行至关重要。目前，已经开发了许多策略来改善血管化过程，其中一些已经显示出很好的潜力，但它们可能离临床应用还很远。最近，负压伤口治疗（NPWT）已广泛应用于临床实践中的伤口护理和管理。据报道，NPWT减少了血管向真皮替代物长入所需的时间，提高了移植物的吸收率，表明了伤口修复的巨大潜力。本文介绍了NPWT和真皮替代品在组织修复和再生中的综合应用。并对相关问题和前景进行了讨论。
In clinical practice, skin defects occur frequently due to various kinds of acute and chronic diseases. The standard treatment for these wounds is autografting, which usually results in complications such as scar formation and new wounds at donor sites. The advent of dermal substitutes has provided a novel method for wound repair, and rapid angiogenesis of the dermal substitutes is crucial for the graft to take. At present, many strategies have been developed to improve the process of vascularisation, some of which have shown promising potentials, but they could be very far from clinical applications. Most recently, negative-pressure wound therapy (NPWT) has been used extensively in clinical practice for wound care and management. It has been reported that NPWT reduces the time required for vascular ingrowth into the dermal substitute and improves graft take, indicating great potentials for wound repair. This article presents a comprehensive overview of the combined use of NPWT and dermal substitutes for tissue repair and regeneration. Relative concerns and prospects are also discussed.
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影响因子：
3
作者：
FOX, JW;GOLDEN, GT
通讯作者：
GOLDEN, GT
DOI：
10.1016/j.bbrc.2007.08.155
发表时间：
2007-11-23
影响因子：
3.1
作者：
Kellouche, Sabrina;Martin, Christophe;Dosquet, Christine
通讯作者：
Dosquet, Christine
影响因子：
3.3
作者：
Huang, S;Chen, CS;Ingber, DE
通讯作者：
Ingber, DE
影响因子：
1.5
作者：
Argenta, LC;Morykwas, MJ
通讯作者：
Morykwas, MJ
影响因子：
2.7
作者：
Hop, M. Jenda;Bloemen, Monica C. T.;Middelkoop, Esther
通讯作者：
Middelkoop, Esther