Wild Zebrafish Sentinels: Biological Monitoring of Site Differences Using Behavior and Morphology.
Wild Zebrafish Sentinels: Biological Monitoring of Site Differences Using Behavior and Morphology.
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DOI：
10.3390/toxics9070165
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发表时间：
2021-07-12
期刊：
影响因子：
4.6
通讯作者：
Shelton DS
中科院分区：
文献类型：
--
作者：
Kelly JR;Shelton SG;Daniel DK;Bhat A;Mondal R;Nipple F;Amro H;Bower ME;Isaac G;McHaney G;Martins EP;Shelton DS
环境变化对人类和环境健康构成了毁灭性的风险。快速评估水情对于监测、评价和处理这一全球健康危险是必要的。哨兵或生物监测仪可以在现场部署，使用最少的资源实时、快速和廉价地检测水质变化。斑马鱼（Danio rerio）是检测环境变化的理想哨兵，因为它们的生物医学工具包，广泛的地理分布和对环境干扰的良好表征的表型反应。在这里，我们通过描述印度两个野外地点之间野生斑马鱼的表型差异来证明斑马鱼哨兵的效用。场地1是一个农村环境，有流动的水，低氧条件，最少的人为碎片，铁和铅浓度高。站点2是一个城市环境，有静水、缺氧条件、塑料污染和高砷、铁和铬浓度。我们发现Site 2的斑马鱼比Site 1的鱼更小，更有凝聚力，更不活跃。我们还在Site 2种群中发现了两性二态的体型，但在Site 1种群中没有。推进斑马鱼前哨研究和开发将能够快速发现、评估和应对新出现的全球健康威胁。
Environmental change poses a devastating risk to human and environmental health. Rapid assessment of water conditions is necessary for monitoring, evaluating, and addressing this global health danger. Sentinels or biological monitors can be deployed in the field using minimal resources to detect water quality changes in real time, quickly and cheaply. Zebrafish (Danio rerio) are ideal sentinels for detecting environmental changes due to their biomedical tool kit, widespread geographic distribution, and well-characterized phenotypic responses to environmental disturbances. Here, we demonstrate the utility of zebrafish sentinels by characterizing phenotypic differences in wild zebrafish between two field sites in India. Site 1 was a rural environment with flowing water, low-hypoxic conditions, minimal human-made debris, and high iron and lead concentrations. Site 2 was an urban environment with still water, hypoxic conditions, plastic pollution, and high arsenic, iron, and chromium concentrations. We found that zebrafish from Site 2 were smaller, more cohesive, and less active than Site 1 fish. We also found sexually dimorphic body shapes within the Site 2, but not the Site 1, population. Advancing zebrafish sentinel research and development will enable rapid detection, evaluation, and response to emerging global health threats.
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影响因子：
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作者：
Bambino K;Chu J
通讯作者：
Chu J
影响因子：
5.6
作者：
Cornet C;Calzolari S;Miñana-Prieto R;Dyballa S;van Doornmalen E;Rutjes H;Savy T;D'Amico D;Terriente J
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2.5
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通讯作者：
Ross, Helen
影响因子：
2.6
作者：
Bhat, A
通讯作者：
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