Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology.
Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology.
复制标题
亚洲蜜蜂中华蜜蜂的基因组和转录组分析为蜜蜂生物学提供了新的见解
DOI：
10.1038/s41598-017-17338-6
复制
发表时间：
2018-01-16
影响因子：
4.6
通讯作者：
Wu J
中科院分区：
文献类型：
--
作者：
Diao Q;Sun L;Zheng H;Zeng Z;Wang S;Xu S;Zheng H;Chen Y;Shi Y;Wang Y;Meng F;Sang Q;Cao L;Liu F;Zhu Y;Li W;Li Z;Dai C;Yang M;Chen S;Chen R;Zhang S;Evans JD;Huang Q;Liu J;Hu F;Su S;Wu J
亚洲蜜蜂 Apis cerana 是商业饲养的两种具有巨大经济价值的蜜蜂之一。在这里，我们介绍了中华蜜蜂的基因组序列分析和转录组学探索，以及亚洲蜜蜂和欧洲蜜蜂蜜蜂的比较基因组分析。基因组和 RNA-seq 数据为了解寄生螨瓦螨的行为和生理抗性、抗菌肽的进化以及中华蜜蜂分工的遗传基础提供了新的见解。两个姐妹物种之间的基因比较揭示了中华蜜蜂特有的基因，其中 54.5% 与任何已知蛋白质没有同源性。与基因表达分析相结合，中华蜜蜂对瓦螨的存在表现出明显更加警惕的梳理行为，这表明中华蜜蜂的寄生虫防御梳理行为可能不仅是通过视觉和嗅觉检测寄生虫的外源刺激触发的，而且还可能是由周期性激活一轮梳理行为以去除外寄生虫的遗传内源过程触发的。这些信息提供了一个有价值的平台，可以促进中华蜜蜂独有的特征以及与其他社会性蜜蜂共享的特征，以改善健康。
The Asian honeybee Apis cerana is one of two bee species that have been commercially kept with immense economic value. Here we present the analysis of genomic sequence and transcriptomic exploration for A. cerana as well as the comparative genomic analysis of the Asian honeybee and the European honeybee A. mellifera. The genome and RNA-seq data yield new insights into the behavioral and physiological resistance to the parasitic mite Varroa the evolution of antimicrobial peptides, and the genetic basis for labor division in A. cerana. Comparison of genes between the two sister species revealed genes specific to A. cerana, 54.5% of which have no homology to any known proteins. The observation that A. cerana displayed significantly more vigilant grooming behaviors to the presence of Varroa than A. mellifera in conjunction with gene expression analysis suggests that parasite-defensive grooming in A. cerana is likely triggered not only by exogenous stimuli through visual and olfactory detection of the parasite, but also by genetically endogenous processes that periodically activates a bout of grooming to remove the ectoparasite. This information provides a valuable platform to facilitate the traits unique to A. cerana as well as those shared with other social bees for health improvement.
登录
查看更多内容
影响因子：
12.3
作者：
Barribeau SM;Sadd BM;du Plessis L;Brown MJ;Buechel SD;Cappelle K;Carolan JC;Christiaens O;Colgan TJ;Erler S;Evans J;Helbing S;Karaus E;Lattorff HM;Marxer M;Meeus I;Näpflin K;Niu J;Schmid-Hempel R;Smagghe G;Waterhouse RM;Yu N;Zdobnov EM;Schmid-Hempel P
通讯作者：
Schmid-Hempel P
影响因子：
3.7
作者：
Arechavaleta-Velasco ME;Alcala-Escamilla K;Robles-Rios C;Tsuruda JM;Hunt GJ
通讯作者：
Hunt GJ
影响因子：
14.9
作者：
Bromberg Y;Rost B
通讯作者：
Rost B
影响因子：
14.2
作者：
Grunwald, T;Bockisch, B;Ollert, MW
通讯作者：
Ollert, MW
影响因子：
4.1
作者：
Arias, MC;Sheppard, WS
通讯作者：
Sheppard, WS