Acculturation is associated with asthma burden and pulmonary function in Latino youth: The GALA II study.
Acculturation is associated with asthma burden and pulmonary function in Latino youth: The GALA II study.
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DOI：
10.1016/j.jaci.2018.12.1015
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发表时间：
2019-05
影响因子：
14.2
通讯作者：
Burchard, Esteban G.
中科院分区：
文献类型：
--
作者：
Thakur, Neeta;Borrell, Luisa N.;Ye, Morgan;Oh, Sam S.;Eng, Celeste;Meade, Kelley;Avila, Pedro C.;Farber, Harold J.;Serebrisky, Denise;Brigino-Buenaventura, Emerita;Rodriguez-Cintron, William;Kumar, Rajesh;Bibbins-Domingo, Kirsten;Thyne, Shannon;Sen, Saunak;Rodriguez-Santana, Jose R.;Burchard, Esteban G.
文化适应是拉美裔年轻人，特别是墨西哥裔美国人患哮喘的重要预测因素。对文化适应和肺功能测量知之甚少。评估文化适应措施与拉美裔青年哮喘和肺功能的相关性，并确定这种相关性是否在拉美裔亚群中有所不同。我们包括来自美国4个城市地区的1,849名拉丁裔(302名加勒比西班牙语人，193名中南美洲人，1,136名墨西哥裔美国人，218名其他拉丁裔儿童)。文化适应测量包括出生状态、移民年龄、偏好语言和在美国的代别。我们使用多变量Logistic和线性回归模型来量化文化适应因素与哮喘的相关性(病例对照研究)和调整人口、社会环境和临床变量的肺功能(仅病例研究)。对于所有的文化适应指标(出生状态、移民年龄、偏爱语言和美国的世代)，文化适应程度越高，患哮喘的几率就越大。在病例中，语言适应水平高(英语偏好)和中等水平(西班牙语和英语同等偏好)与低水平(西班牙语偏好)相比，支气管扩张剂反应降低(p分别为0.009和0.02)。同样，与低语言适应相比，高语言适应与FEV1增加相关(p=0.02)。没有足够的证据表明拉丁裔亚群之间的联系是异质性的。在拉美裔儿童中，文化适应与确诊的哮喘和肺功能有关，是治疗患有哮喘的拉美裔青年时需要考虑的重要因素。在拉美人中，高文化背景会增加诊断为哮喘的可能性，而低文化背景则与肺功能降低和支气管扩张剂反应增强有关；在确定风险和管理哮喘时，应考虑文化和行为实践。
Acculturation is an important predictor of asthma in Latino youth, specifically, Mexican Americans. Less is known about acculturation and pulmonary function measures. To estimate the association of acculturation measures with asthma and pulmonary function in Latino youth and determine whether this association varies across Latino subgroups. We included 1,849 Latinos (302 Caribbean Spanish, 193 Central or South Americans, 1,136 Mexican Americans, 218 other Latino children) aged 8–21 years old from 4 urban regions in the U.S. Acculturation measures include nativity status, age of immigration, language of preference, and generation in the U.S. We used multivariable logistic and linear regression models to quantify the association of acculturation factors with the presence of asthma (case-control study) and pulmonary function (case-only study) adjusting for demographic, socio-environmental, and clinical variables. For all acculturation measures (nativity status, age of immigration, language of preference, and generation in the U.S.), higher levels of acculturation were associated with greater odds of asthma. Among cases, high (English preference) and medium (equal preference for Spanish and English) levels of language acculturation were associated with decreased bronchodilator response compared with low (Spanish preference) levels (p=0.009 and 0.02, respectively). Similarly, high language acculturation was associated with increased FEV1 compared with low language acculturation (p=0.02). There was insufficient evidence of heterogeneity for associations across Latino subgroups. Acculturation was associated with diagnosed asthma and pulmonary function in Latino children and is important factor to consider in the management of Latino youth with asthma. High acculturation increases likelihood of diagnosed asthma whereas low acculturation is associated with lower pulmonary function and increased bronchodilator response in Latinos; cultural and behavioral practices should be considered when determining risk and managing asthma.
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影响因子：
1.9
作者：
Eldeirawi, Kamal;McConnell, Rob;Persky, Victoria W.
通讯作者：
Persky, Victoria W.
DOI：
10.1111/cea.12765
发表时间：
2016-11
期刊：
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
影响因子：
--
作者：
Abid Z;Oh SS;Hu D;Sen S;Huntsman S;Eng C;Farber HJ;Rodriguez-Cintron W;Rodriguez-Santana JR;Serebrisky D;Avila PC;Thyne SM;Kim KA;Borrell LN;Williams LK;Seibold MA;Burchard EG;Kumar R
通讯作者：
Kumar R
影响因子：
2.5
作者：
Gibson, MV;Diaz, VA;Geesey, ME
通讯作者：
Geesey, ME
影响因子：
12.7
作者：
Abraído-Lanza, AF;Dohrenwend, BP;Turner, JB
通讯作者：
Turner, JB
DOI：
10.1891/1540-4153.13.3.119
发表时间：
2015-01-01
期刊：
Hispanic health care international : the official journal of the National Association of Hispanic Nurses
影响因子：
--
作者：
Chavez-Payan, Paola;Grineski, Sara E;Collins, Timothy W
通讯作者：
Collins, Timothy W