Hypothesis on the Dual Origin of the Mammalian Subplate
Hypothesis on the Dual Origin of the Mammalian Subplate
复制标题
哺乳动物亚板块双重起源假说
作者：
J. Montiel;Wei Zhi Wang;Franziska M. Oeschger;A. Hoerder;Wan Ling Tung;F. García;I. Holm;Aldo Villalón;Z. Molnár
哺乳动物新皮层的发育在很大程度上依赖于基板。这种细胞群的比例在不同的哺乳动物物种中变化很大。基板在有袋动物中几乎无法检测到，在小鼠和大鼠中形成薄但明显的层，在食肉动物和猪等脑大的哺乳动物中形成较大的层，在人类和非人类灵长类动物中形成高度发达的胚胎结构。亚板神经元的进化起源是目前争论的主题。一些人假设亚板代表蜥脚类动物的祖先皮层，而另一些人则认为它是哺乳动物新皮层的一个越来越复杂的系统发育新奇。在这里，我们回顾了最近的几个基因的表达，最初确定在啮齿动物中高度和差异表达的亚板。我们将这些观察结果与几个物种的背侧皮层/背侧软腭的细胞形态，出生日期和hodology。根据这一审查的证据，我们认为第三个假设，根据该亚板包含祖先和新衍生的细胞群体。我们建议，哺乳动物的亚板最初来自于一个在背palaleums的干paleums的遗传古老的结构，但随后扩大了额外的细胞群中的synapsid谱系，以支持越来越复杂的皮质板的发展。进一步了解详细的分子分类学，体树突形态学，并在比较上下文中的连接subplate应有助于识别的祖先和新进化的种群subplate神经元。
The development of the mammalian neocortex relies heavily on subplate. The proportion of this cell population varies considerably in different mammalian species. Subplate is almost undetectable in marsupials, forms a thin, but distinct layer in mouse and rat, a larger layer in carnivores and big-brained mammals as pig, and a highly developed embryonic structure in human and non-human primates. The evolutionary origin of subplate neurons is the subject of current debate. Some hypothesize that subplate represents the ancestral cortex of sauropsids, while others consider it to be an increasingly complex phylogenetic novelty of the mammalian neocortex. Here we review recent work on expression of several genes that were originally identified in rodent as highly and differentially expressed in subplate. We relate these observations to cellular morphology, birthdating, and hodology in the dorsal cortex/dorsal pallium of several amniote species. Based on this reviewed evidence we argue for a third hypothesis according to which subplate contains both ancestral and newly derived cell populations. We propose that the mammalian subplate originally derived from a phylogenetically ancient structure in the dorsal pallium of stem amniotes, but subsequently expanded with additional cell populations in the synapsid lineage to support an increasingly complex cortical plate development. Further understanding of the detailed molecular taxonomy, somatodendritic morphology, and connectivity of subplate in a comparative context should contribute to the identification of the ancestral and newly evolved populations of subplate neurons.
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皮质目标耗竭和膝皮质轴突向内生长：对皮质规范的影响。
DOI：
10.1093/cercor/6.3.457
发表时间：
1996
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
Woo,TU;Finlay,BL
通讯作者：
Finlay,BL
纯化的皮质亚板神经元中的突触发生。
DOI：
10.1093/cercor/bhn194
发表时间：
2009
期刊：
Cerebral cortex (New York, N.Y. : 1991)
影响因子：
--
作者：
McKellar,ClaireE;Shatz,CarlaJ
通讯作者：
Shatz,CarlaJ
影响因子：
56.9
作者：
Catalano, SM;Shatz, CJ
通讯作者：
Shatz, CJ
DOI：
--
发表时间：
--
期刊：
--
影响因子：
--
作者：
S. W. Grill;P. Gönczy;E. H. K. Stelzer;A. Hyman;D J Sharp;G. C. Rogers;J. Scholey;M Gotta;Y. Dong;Y. K. Peterson;S. M. Lanier;J. Ahringer;R. G. M. Srinivasan;H. Fisk;S. Xu;Den Van;Heuvel;A. Cowan;M. Desai;P. Diehl;M. Gönczy;E. Glotzer;F. Hannak;K. Jülicher;L. Oegema;A. Pelletier;G. Riedinger;E. Ritter;N. Sackmann;M. Salmon;E. Srayko;Tanaka;P. Kanold;Prakash Kara;R. Clay;Reid;C. Shatz
通讯作者：
S. W. Grill;P. Gönczy;E. H. K. Stelzer;A. Hyman;D J Sharp;G. C. Rogers;J. Scholey;M Gotta;Y. Dong;Y. K. Peterson;S. M. Lanier;J. Ahringer;R. G. M. Srinivasan;H. Fisk;S. Xu;Den Van;Heuvel;A. Cowan;M. Desai;P. Diehl;M. Gönczy;E. Glotzer;F. Hannak;K. Jülicher;L. Oegema;A. Pelletier;G. Riedinger;E. Ritter;N. Sackmann;M. Salmon;E. Srayko;Tanaka;P. Kanold;Prakash Kara;R. Clay;Reid;C. Shatz
影响因子：
56.9
作者：
Anderson, SA;Eisenstat, DD;Rubenstein, JLR
通讯作者：
Rubenstein, JLR