Vapor deposition synthesis of polypyrrole nanoparticles with a tunable photothermal conversion capacity

Vapor deposition synthesis of polypyrrole nanoparticles with a tunable photothermal conversion capacity
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气相沉积合成具有可调光热转换能力的聚吡咯纳米粒子

DOI:
10.1016/j.colsurfa.2020.126073
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发表时间:
2021-03
期刊:
Colloids and Surfaces A: Physicochemical and Engineering Aspects
影响因子:
--
通讯作者:
Duowu Zou
Duowu Zou
中科院分区:
其他
文献类型:
--
作者:
Chunhua Zhou;Yao Zhang;Feihu Yan;Yizhou Zhao;Shige Wang;Bingqian Guo;Jia He;Duowu Zou

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In recent years, nanomaterials have aroused people's interest in the field of biomedicine. Polypyrrole (PPy) has become a research hotspot because of its simple synthesis, excellent photothermal conversion performance, and high biocompatibility. Here, we report the synthesis of PPy nanoparticles (PPy-PVP NPs) using a vapor deposition method, for tumor photothermal therapy. In this method, the slowly produced volatile pyrrole vapor was absorbed by the PVP (polyvinylpyrrolidone)/FeCl3aqueous solution. This slow vapor production and absorption allows the formation of uniform PPy-PVP NPs at room temperature. Then, the effects of the molecular weight of PVP on the photothermal property and anti-tumor efficiency of PPy-PVP NPs were compared. It was found that the selection of PVP40kDaas the template and surface linker can ensure a better application performance of the synthesized nanomaterials. This work provides a theoretical basis for the rational design of nano-therapy carriers and biomedical applications.
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