Historical trends in modifiable indicators of cardiovascular health and self-rated health among older adults: Cohort differences over 20 years between the Berlin Aging Study (BASE) and the Berlin Aging Study II (BASE-II).

Historical trends in modifiable indicators of cardiovascular health and self-rated health among older adults: Cohort differences over 20 years between the Berlin Aging Study (BASE) and the Berlin Aging Study II (BASE-II).
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DOI:
10.1371/journal.pone.0191699
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发表时间:
2018
期刊:
影响因子:
3.7
通讯作者:
Demuth I
Demuth I
中科院分区:
综合性期刊3区
文献类型:
--
作者:
König M;Drewelies J;Norman K;Spira D;Buchmann N;Hülür G;Eibich P;Wagner GG;Lindenberger U;Steinhagen-Thiessen E;Gerstorf D;Demuth I

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过去几十年来,人们对心血管疾病 (CVD) 的认识、治疗和预防取得了巨大进步。尽管过去几十年来,CVD 引起的死亡率已显着下降,但 CVD 的负担仍然很高,尤其是老年人。这就提出了一个问题:与较早出生的人群相比,当代老年人群的客观和主观健康状况是否更好或更差。本研究的目的是通过比较柏林老龄化研究(BASE,1990-93)和柏林老龄化研究 II(BASE-II,2009-2014)中相隔 20 年获得的数据,探讨可修改的心血管健康指标(CVH)的差异。对 BASE(出生于 1907-1922 年)和 BASE-II(出生于 1925-1942 年)的 242 名倾向得分匹配参与者进行系列横断面分析。体重指数(BMI)、血压、总胆固醇、糖化血红蛋白(HbA1c)、饮食、吸烟和体力活动均根据美国心脏协会的“Life's simple 7”(LS7)标准进行操作。根据年龄、性别和教育程度确定了 121 对匹配的人。在较晚出生的 BASE-II 样本中,平均 LS7 评分显着高于较早出生的样本(7.8±1.8 vs. 6.4±2.1,p<0.001),表明 CVH 更好。具体来说,饮食、体力活动、吸烟、胆固醇和糖化血红蛋白 (HbA1c) 更有利,而晚出生队列中的个体的血压则明显更高。两个匹配样本之间的 BMI 没有显着差异。值得注意的是,尽管有更好的 CVH,但较晚出生的个体 (BASE-II) 报告的健康自我评价较低,大概是因为较高的健康期望。总体而言,晚出生人群的心血管健康状况明显更好,但也存在一些值得注意的例外。
The last decades have seen great advances in the understanding, treatment, and prevention of cardiovascular disease (CVD). Although mortality rates due to CVD have declined significantly in the last decades, the burden of CVD is still high, particularly in older adults. This raises the question whether contemporary populations of older adults are experiencing better or worse objective as well as subjective health than earlier-born cohorts. The aim of this study was to examine differences in modifiable indicators of cardiovascular health (CVH), comparing data obtained 20 years apart in the Berlin Aging Study (BASE, 1990–93) and the Berlin Aging Study II (BASE-II, 2009–2014). Serial cross-sectional analysis of 242 propensity-score-matched participants of BASE (born 1907–1922) and BASE-II (born 1925–1942). Body mass index (BMI), blood pressure, total cholesterol, glycated hemoglobin (HbA1c), diet, smoking and physical activity were operationalized according to the “Life’s simple 7“(LS7) criteria of the American Heart Association. 121 matched pairs were identified based on age, sex, and education. In the later-born BASE-II sample, the mean LS7 score was significantly higher than in the earlier-born sample (7.8±1.8 vs. 6.4±2.1, p<0.001), indicating better CVH. In detail, diet, physical activity, smoking, cholesterol, and HbA1c were more favorable, whereas blood pressure was significantly higher in individuals from the later-born cohort. BMI did not differ significantly between the two matched samples. Notably, despite better CVH, later-born individuals (BASE-II) reported lower self-rated health, presumably because of higher health expectations. Overall, cardiovascular health was significantly better in the later-born cohort, but several notable exceptions exist.
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