Wireless and battery-free technologies for neuroengineering.

Wireless and battery-free technologies for neuroengineering.
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DOI:
10.1038/s41551-021-00683-3
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发表时间:
2023-04
影响因子:
28.1
通讯作者:
Rogers JA
Rogers JA
中科院分区:
工程技术1区
文献类型:
--
作者:
Won SM;Cai L;Gutruf P;Rogers JA

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Tethered optical, electrical and fluidic battery-powered devices that interface with neural tissue constrain or prevent subject motion, as well as social interactions, and prevent their long-term use in larger models, such as non-human primates, which inhabit complex environments, move over large distances and have high levels of manual dexterity. Here, we discuss recent advances in ultra-lightweight, miniaturized, wireless and battery-free devices that are fully implantable, with capabilities that match or exceed the performance of tethered and battery-powered alternatives, while bypassing their intrinsic limitations. These systems enable closed-loop applications that combine neural recordings and neurostimulation and include the long-lived delivery of therapeutic compounds and the real-time monitoring and treatment of abnormal physiological functions. Recent advances in material science and neuroengineering serve as the foundations for lightweight, miniaturized and fully implantable wireless devices that interface with biological tissues for recording and stimulating neural activity, without the need for batteries or physical tethers.
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