An analysis and systematic review of sarcopenia increasing osteopenia risk.
An analysis and systematic review of sarcopenia increasing osteopenia risk.
复制标题
对肌肉减少症增加骨质减少风险的分析和系统评价。
DOI：
10.1371/journal.pone.0250437
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Lu S
中科院分区：
文献类型：
--
作者：
Teng Z;Zhu Y;Yu X;Liu J;Long Q;Zeng Y;Lu S
Sarcopenia is a progressive generalized skeletal muscle disorder, which may increase the risk of osteopenia. The aim of this study was to systematically review studies on the association between sarcopenia and osteopenia by pooled analysis. The PubMed and Embase databases were searched from inception to October 2020 for studies focusing on the association between sarcopenia and osteopenia. Two reviewers independently extracted data and assessed study quality. A pooled analysis was performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) using random-effects models. Subgroup analysis was conducted to explore the source of heterogeneity and the stability of outcome. A total of 25 independent studies involving 47,744 participants fulfilled the inclusion criteria. Sarcopenia significantly increased the risk of osteopenia (OR, 2.08; 95% CI, 1.66–2.60); Sensitivity analyses indicated the outcome was stable. Subgroup analyses showed that sarcopenia significantly increased osteopenia risk in each subgroup. No evidence of publication bias among the studies existed. In this study, our findings showed that sarcopenia significantly increased the risk of osteopenia. Thus, we suggest that sarcopenia can be a predictor of osteopenia risk.
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影响因子：
4.7
作者：
Maurel DB;Jähn K;Lara-Castillo N
通讯作者：
Lara-Castillo N
影响因子：
4
作者：
He, H.;Liu, Y.;Deng, H. -W.
通讯作者：
Deng, H. -W.
DOI：
10.1590/2359-3997000000011
发表时间：
2015-02-01
期刊：
Archives of Endocrinology and Metabolism
影响因子：
--
作者：
Pereira, Fernando Borges;Leite, André Ferreira;Paula, Ana Patrícia de
通讯作者：
Paula, Ana Patrícia de
DOI：
10.5114/reum.2017.71627
发表时间：
2017-01-01
期刊：
Reumatologia (Warsaw)
影响因子：
--
作者：
Krajewska-Wlodarczyk, Magdalena;Owczarczyk-Saczonek, Agnieszka;Placek, Waldemar
通讯作者：
Placek, Waldemar
DOI：
10.1016/0197-2456(86)90046-2
发表时间：
1986-09-01
期刊：
CONTROLLED CLINICAL TRIALS
影响因子：
--
作者：
DERSIMONIAN, R;LAIRD, N
通讯作者：
LAIRD, N