Emotional processing in anterior cingulate and medial prefrontal cortex.

Emotional processing in anterior cingulate and medial prefrontal cortex.
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DOI:
10.1016/j.tics.2010.11.004
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发表时间:
2011-02
影响因子:
19.9
通讯作者:
Kalisch, Raffael
Kalisch, Raffael
中科院分区:
心理学1区
文献类型:
--
作者:
Etkin, Amit;Egner, Tobias;Kalisch, Raffael

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负面情绪刺激激活了一个广泛的网络,包括内侧前额叶(mPFC)和前扣带(ACC)皮质。早期有一种有影响力的观点将这些区域一分为二,分为背-尾“认知”和腹-吻“情感”两个亚区。在这篇综述中,我们研究了丰富的最近的研究在动物和人类的负面情绪,使用的例子恐惧/焦虑,并得出结论,与传统的二分法,这两个细分作出关键贡献的情绪处理。具体而言,背尾侧区域的ACC/mPFC参与评价和表达的负面情绪,而腹侧-喙侧部分的ACC/mPFC具有调节作用,相对于边缘区域参与产生情绪反应。此外,这一新框架与其他消极和积极情绪的新数据大致一致。
Negative emotional stimuli activate a broad network, including the medial prefrontal (mPFC) and anterior cingulate (ACC) cortices. An early influential view dichotomized these regions into dorsal-caudal “cognitive” and ventral-rostral “affective” subdivisions. In this review, we examine a wealth of recent research on negative emotions in animals and humans, using the example of fear/anxiety, and conclude that, contrary to the traditional dichotomy, both subdivisions make key contributions to emotional processing. Specifically, dorsal-caudal regions of the ACC/mPFC are involved in appraisal and expression of negative emotion, while ventral-rostral portions of the ACC/mPFC have a regulatory role with respect to limbic regions involved in generating emotional responses. Moreover, this new framework is broadly consistent with emerging data on other negative and positive emotions.
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