The neural basis of inhibitory effects of semantic and phonological neighbors in spoken word production.
The neural basis of inhibitory effects of semantic and phonological neighbors in spoken word production.
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DOI：
10.1162/jocn_a_00408
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发表时间：
2013-09
影响因子：
3.2
通讯作者：
Graziano KM
中科院分区：
文献类型：
--
作者：
Mirman D;Graziano KM
单词产生和单词识别的理论通常认为在处理过程中会激活多个候选单词。人们已经使用行为方法对这些“词汇邻居”的促进和抑制作用进行了广泛的研究，并刺激了心理语言学的理论发展，但人们对这些作用的神经基础以及病变如何影响它们的了解相对较少。本研究使用体素损伤重叠减法来检查左半球中风后口语产生中的语义和语音邻居效应。邻近语义邻居的抑制作用增强与下额叶病变相关，这表明在强烈激活的语义相关候选者中的选择受损。语音邻居的抑制作用增强与颞上后部和顶下叶病变有关。与之前的研究相结合，这些结果表明，这种损伤会导致语音到词汇的反馈，从而更强烈地激活语音相关的候选词汇。语义和语音邻居效应的比较以及它们如何受到左半球病变的影响，为口语产生中语音、语义和认知控制过程的认知动力学和神经基础提供了新的见解。
Theories of word production and word recognition generally agree that multiple word candidates are activated during processing. The facilitative and inhibitory effects of these “lexical neighbors” have been studied extensively using behavioral methods and have spurred theoretical development in psycholinguistics, but relatively little is known about the neural basis of these effects and how lesions may affect them. The present study used voxel-wise lesion overlap subtraction to examine semantic and phonological neighbor effects in spoken word production following left hemisphere stroke. Increased inhibitory effects of near semantic neighbors were associated with inferior frontal lobe lesions, suggesting impaired selection among strongly activated semantically-related candidates. Increased inhibitory effects of phonological neighbors were associated with posterior superior temporal and inferior parietal lobe lesions. In combination with previous studies, these results suggest that such lesions cause phonological-to-lexical feedback to more strongly activate phonologically-related lexical candidates. The comparison of semantic and phonological neighbor effects and how they are affected by left hemisphere lesions provides new insights into the cognitive dynamics and neural basis of phonological, semantic, and cognitive control processes in spoken word production.
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影响因子：
3.6
作者：
Kemmerer, David;Rudrauf, David;Manzel, Ken;Tranel, Daniel
通讯作者：
Tranel, Daniel
影响因子：
25
作者：
Badre, David;Hoffman, Joshua;Cooney, Jeffrey W.;D'Esposito, Mark
通讯作者：
D'Esposito, Mark
DOI：
10.1016/j.cortex.2012.03.001
发表时间：
2013-03
期刊：
Cortex; a journal devoted to the study of the nervous system and behavior
影响因子：
--
作者：
Baldo JV;Arévalo A;Patterson JP;Dronkers NF
通讯作者：
Dronkers NF
影响因子：
10.9
作者：
Avants, Brian B.;Schoenemann, P. Thomas;Gee, James C.
通讯作者：
Gee, James C.
影响因子：
2.5
作者：
Buchsbaum, Bradley R.;Baldo, Juliana;Hickok, Gregory
通讯作者：
Hickok, Gregory