Retrospective respiratory self-gating and removal of bulk motion in pulmonary UTE MRI of neonates and adults.
Retrospective respiratory self-gating and removal of bulk motion in pulmonary UTE MRI of neonates and adults.
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DOI：
10.1002/mrm.26212
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发表时间：
2017-03
影响因子：
3.3
通讯作者：
Woods, Jason C.
中科院分区：
文献类型：
--
作者：
Higano, Nara S.;Hahn, Andrew D.;Tkach, Jean A.;Cao, Xuefeng;Walkup, Laura L.;Thomen, Robert P.;Merhar, Stephanie L.;Kingma, Paul S.;Fain, Sean B.;Woods, Jason C.
对非镇静、自由呼吸的新生儿和成人进行肺部 3D 径向超短回波时间 (UTE) MRI，并对呼吸和间歇性整体运动进行回顾性运动跟踪，以获得诊断质量的呼吸门控图像。在新生儿和成人志愿者自由呼吸期间以 1.5T 进行肺部 3D 径向 UTE MRI 进行验证。运动跟踪波形是从每个自由感应衰变的初始点（即 k 空间中心）的时间过程中获得的，允许呼吸门控图像重建，排除在体运动期间获取的数据。潮气量是根据呼气末和吸气末图像计算的。呼吸频率是根据安静呼吸期间运动跟踪波形的傅立叶变换计算出来的，与新生儿的生理预测进行比较，并通过成人肺量测定法进行验证。在吸气和呼气时获得高质量的呼吸门控解剖图像，以牺牲更窄的门控窗口的信噪比为代价减少呼吸模糊。吸气-呼气量差异与生理预测（新生儿；Bland-Altman 偏差 = 6.2 mL）和肺量测定值（成人；偏差 = 0.11 L）一致。 MRI 测量的呼吸频率与观察到的呼吸频率相比（新生儿和成人的偏差分别为 -0.5 次和 0.2 次呼吸/分钟）。 3D 径向肺 UTE MRI 允许对自由呼吸、未镇静的新生儿和成人进行回顾性呼吸自门控并消除间歇性大量运动。
To implement pulmonary 3D radial ultrashort echo-time (UTE) MRI in non-sedated, free-breathing neonates and adults with retrospective motion-tracking of respiratory and intermittent bulk motion, to obtain diagnostic-quality, respiratory-gated images. Pulmonary 3D radial UTE MRI was performed at 1.5T during free-breathing in neonates and adult volunteers for validation. Motion-tracking waveforms were obtained from the time-course of each free induction decay’s initial point (i.e. k-space center), allowing for respiratory-gated image reconstructions that excluded data acquired during bulk motion. Tidal volumes were calculated from end-expiration and end-inspiration images. Respiratory rates were calculated from the Fourier transform of the motion-tracking waveform during quiet-breathing, with comparison to physiologic prediction in neonates and validation with spirometry in adults. High-quality respiratory-gated anatomic images were obtained at inspiration and expiration, with less respiratory blurring at the expense of signal-to-noise for narrower gating windows. Inspiration-expiration volume differences agreed with physiologic predictions (neonates; Bland-Altman bias = 6.2 mL) and spirometric values (adults; bias = 0.11 L). MRI-measured respiratory rates compared well with observed rates (biases = −0.5 and 0.2 breaths/min for neonates and adults, respectively). 3D radial pulmonary UTE MRI allows for retrospective respiratory self-gating and removal of intermittent bulk motion in free-breathing, non-sedated neonates and adults.
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影响因子：
3.3
作者：
Hatabu, H;Alsop, DC;Gefter, WB
通讯作者：
Gefter, WB
影响因子：
2.8
作者：
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通讯作者：
Harris, Christine
影响因子：
19.7
作者：
Dournes, Gael;Grodzki, David;Laurent, Francois
通讯作者：
Laurent, Francois
影响因子：
5
作者：
Ohno, Yoshiharu;Koyama, Hisanobu;Sugimura, Kazuro
通讯作者：
Sugimura, Kazuro
影响因子：
2.9
作者：
Bianchi, Andrea;Dufort, Sandrine;Cremillieux, Yannick
通讯作者：
Cremillieux, Yannick