A workflow for predicting temperature increase at the electrical contacts of deep brain stimulation electrodes undergoing MRI.
A workflow for predicting temperature increase at the electrical contacts of deep brain stimulation electrodes undergoing MRI.
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DOI：
10.1002/mrm.29375
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发表时间：
2022-11
影响因子：
3.3
通讯作者：
Eryaman, Yigitcan
中科院分区：
文献类型：
--
作者：
Sadeghi-Tarakameh, Alireza;Zulkarnain, Nur Izzati Huda;He, Xiaoxuan;Atalar, Ergin;Harel, Noam;Eryaman, Yigitcan
本研究的目的是提供一种预测MRI扫描期间脑深部电刺激（DBS）电极导线触点周围射频（RF）发热的工作流程。DBS电极导线上的感应射频电流会在金属触点上积累电荷，这可能会导致局部比吸收率（SAR）较高，从而导致发热。通过在准静态电磁（EM）模拟中对触点施加电压边界条件，对累积电荷进行建模，从而允许使用所得SAR分布进行热模拟。考虑到解剖结构差异和电极导线几何形状的变化，通过EM模拟估计体内电极导线的SAR和温升不切实际。为了克服这一局限性，定义了一个新的参数transsimplity来表征给定的电极导线。通过结合跨阻抗（可以在单次校准扫描中测量）沿着电极导线在独特方向和解剖结构中的基于MR的电流测量值，可以估计局部发热。将采用这种方法确定的致热与凝胶体模中具有不同电极导线配置的商业DBS电极的致热研究结果进行比较，以验证所提出的方法。使用来自单个校准实验的数据，确定市售DBS电极（定向电极导线，Infinity DBS系统，Abbott Laboratories，芝加哥，IL）的跨阻抗为88 Ω。在26种不同电极导线配置中，使用DBS跨阻抗和快速采集的基于MR的电流测量值进行的发热预测与RF扫描期间的实验发热测量值相比，归一化均方根误差<23%（平均11.3%）。在本研究中，提出了一种工作流程，包括DBS电极导线上基于MR的电流测量和简单的准静态EM/热模拟，以预测接受MRI扫描的DBS电极周围的温度升高，并使用市售DBS电极进行了确认。 点击此处进行作者-读者讨论
The purpose of this study is to present a workflow for predicting the radiofrequency (RF) heating around the contacts of a deep brain stimulation (DBS) lead during an MRI scan. The induced RF current on the DBS lead accumulates electric charge on the metallic contacts, which may cause a high local specific absorption rate (SAR), and therefore, heating. The accumulated charge was modeled by imposing a voltage boundary condition on the contacts in a quasi‐static electromagnetic (EM) simulation allowing thermal simulations to be performed with the resulting SAR distributions. Estimating SAR and temperature increases from a lead in vivo through EM simulation is not practical given anatomic differences and variations in lead geometry. To overcome this limitation, a new parameter, transimpedance, was defined to characterize a given lead. By combining the transimpedance, which can be measured in a single calibration scan, along with MR‐based current measurements of the lead in a unique orientation and anatomy, local heating can be estimated. Heating determined with this approach was compared with results from heating studies of a commercial DBS electrode in a gel phantom with different lead configurations to validate the proposed method. Using data from a single calibration experiment, the transimpedance of a commercial DBS electrode (directional lead, Infinity DBS system, Abbott Laboratories, Chicago, IL) was determined to be 88 Ω. Heating predictions using the DBS transimpedance and rapidly acquired MR‐based current measurements in 26 different lead configurations resulted in a <23% (on average 11.3%) normalized root‐mean‐square error compared to experimental heating measurements during RF scans. In this study, a workflow consisting of an MR‐based current measurement on the DBS lead and simple quasi‐static EM/thermal simulations to predict the temperature increase around a DBS electrode undergoing an MRI scan is proposed and validated using a commercial DBS electrode. Click here for author‐reader discussions
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