Neural processing of dynamic emotional facial expressions in psychopaths.
Neural processing of dynamic emotional facial expressions in psychopaths.
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DOI：
10.1080/17470919.2013.866905
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发表时间：
2014-02
影响因子：
2
通讯作者：
Kiehl KA
中科院分区：
文献类型：
--
作者：
Decety J;Skelly L;Yoder KJ;Kiehl KA
面部表情通过引起观察者的快速反应，在社交互动中发挥着关键作用。无法感知和体验正常范围和深度的情感会严重影响人际沟通和人际关系。正如已经在许多领域证明的那样，精神病患者的异常情绪处理在他们缺乏同理心方面起着关键作用。然而，神经成像文献并不清楚缺陷是否特定于特定的情绪，如恐惧，或许还有悲伤。此外，不同研究的结果并不一致。在目前的实验中，80名成年监禁男性在野兔精神病检查表-修订版(PCL-R)上得到高、中、低分，并接受了fMRI扫描，同时观察了恐惧、悲伤、快乐和痛苦的动态面部表情。PCL-R得分高的参与者对面部加工网络(枕下回、梭形回、STS)以及扩展网络(额叶下回和眼眶额叶皮质)中所有四种面部表情的神经血液动力学反应都有所降低，这支持了跨情绪领域的普遍缺陷。出乎意料的是，精神病患者的背侧脑岛对恐惧、悲伤和疼痛的反应比非精神病患者更大。重要的是，眼眶前额叶皮质和前额叶腹内侧皮质，这两个与情感和动机行为密切相关的区域，在精神病患者对所有四种情绪表达的感知过程中，明显不那么活跃。
Facial expressions play a critical role in social interactions by eliciting rapid responses in the observer. Failure to perceive and experience a normal range and depth of emotion seriously impact interpersonal communication and relationships. As has been demonstrated across a number of domains, abnormal emotion processing in individuals with psychopathy plays a key role in their lack of empathy. However, the neuroimaging literature is unclear as to whether deficits are specific to particular emotions such as fear and perhaps sadness. Moreover, findings are inconsistent across studies. In the current experiment, eighty adult incarcerated males scoring high, medium, and low on the Hare Psychopathy Checklist-Revised (PCL-R) underwent fMRI scanning while viewing dynamic facial expressions of fear, sadness, happiness and pain. Participants who scored high on the PCL-R showed a reduction in neuro-hemodynamic response to all four categories of facial expressions in the face processing network (inferior occipital gyrus, fusiform gyrus, STS) as well as the extended network (inferior frontal gyrus and orbitofrontal cortex), which supports a pervasive deficit across emotion domains. Unexpectedly, the response in dorsal insula to fear, sadness and pain was greater in psychopaths than non-psychopaths. Importantly, the orbitofrontal cortex and ventromedial prefrontal cortex, regions critically implicated in affective and motivated behaviors, were significantly less active in individuals with psychopathy during the perception of all four emotional expressions.
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影响因子：
16.2
作者：
Breiter, HC;Etcoff, NL;Rosen, BR
通讯作者：
Rosen, BR
影响因子：
5.7
作者：
Banissy, Michael J.;Kanai, Ryota;Walsh, Vincent;Rees, Geraint
通讯作者：
Rees, Geraint
影响因子：
5.7
作者：
de Oliveira-Souza, Ricardo;Hare, Robert D.;Moll, Jorge
通讯作者：
Moll, Jorge
影响因子：
5.7
作者：
Botvinick, M;Jha, AP;Prkachin, KM
通讯作者：
Prkachin, KM
DOI：
10.1111/j.1749-6632.2010.05445.x
发表时间：
2010-01-01
期刊：
YEAR IN COGNITIVE NEUROSCIENCE 2010
影响因子：
--
作者：
Adolphs, Ralph
通讯作者：
Adolphs, Ralph