Atherogenic dyslipidemia and cardiovascular risk factors in obese children.

Atherogenic dyslipidemia and cardiovascular risk factors in obese children.
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DOI:
10.1155/2015/912047
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发表时间:
2015
影响因子:
2.8
通讯作者:
Nobili V
Nobili V
中科院分区:
医学4区
文献类型:
--
作者:
D'Adamo E;Guardamagna O;Chiarelli F;Bartuli A;Liccardo D;Ferrari F;Nobili V

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儿童肥胖与血清脂蛋白变化相关时触发动脉粥样硬化。有证据表明,动脉粥样硬化过程始于儿童时期,主动脉和冠状动脉的早期动脉粥样硬化程度可能与脂蛋白水平和肥胖有关。此外,许多儿童研究表明,胰岛素敏感性参数、体脂分布和脂质异常的发展之间存在重要关系。本文综述了儿童肥胖、血脂异常和心血管风险之间关系的最新研究结果。
Childhood obesity when associated with serum lipoprotein changes triggers atherosclerosis. Evidences suggest that the atherosclerotic process begins in childhood and that the extent of early atherosclerosis of the aorta and coronary arteries can be associated with lipoprotein levels and obesity. Furthermore, many studies in childhood demonstrate an important relationship between parameters of insulin sensitivity, body fat distribution, and the development of lipid abnormalities. This review focuses on the most recent findings on the relationship between obesity, dyslipidemia, and cardiovascular risk in children.
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