Children's internalizing symptoms: the role of interactions between cortisol and respiratory sinus arrhythmia.

Children's internalizing symptoms: the role of interactions between cortisol and respiratory sinus arrhythmia.
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DOI:
10.1016/j.physbeh.2011.02.004
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发表时间:
2011-05-03
影响因子:
2.9
通讯作者:
Erath, Stephen A.
Erath, Stephen A.
中科院分区:
医学3区
文献类型:
--
作者:
El-Sheikh, Mona;Arsiwalla, Dilbur D.;Hinnant, J. Benjamin;Erath, Stephen A.

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我们研究了儿童生理活动在两个系统之间的相互作用,下丘脑-垂体-肾上腺(HPA)轴和副交感神经系统(PNS),作为儿童报告的内化症状(抑郁,焦虑)的预测因子。HPA活性以基线唾液皮质醇为指标,PNS活性以基线呼吸性窦性心律失常(RSA)为指标。研究1包括57名儿童(54%为女孩; M年龄= 8.81岁± 0.34岁),研究2包括219名儿童(51%为女孩; M年龄= 9.31岁± 0.79岁)。皮质醇与RSA相互作用,以解释儿童内化症状的独特差异。在这两项研究中,皮质醇水平较高的儿童与RSA水平较高的儿童往往表现出最低水平的抑郁和焦虑症状。研究结果表明,同时考虑跨多个系统的生理活动可以促进对儿童内化症状的理解。
We examined interactions between children’s physiological activity across two systems, the hypothalamic-pituitary-adrenal (HPA)-axis and the parasympathetic nervous system (PNS), as predictors of child-reported internalizing symptoms (depression, anxiety). HPA activity was indexed by baseline salivary cortisol, and PNS activity was indexed by baseline respiratory sinus arrhythmia (RSA). Study 1 consisted of 57 children (54% girls; M age = 8.81 years ±.34), and Study 2 included 219 children (51% girls; M age = 9.31 years ±.79). Cortisol interacted with RSA to explain unique variance in children’s internalizing symptoms. Across the two studies, children with higher cortisol levels in conjunction with higher RSA levels tended to exhibit the lowest levels of depression and anxiety symptoms. Findings demonstrate that contemporaneous consideration of physiological activity across multiple systems can advance understanding of internalizing symptoms in children.
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