Influence of acidity and auxiliary electrode reaction on the oxidation of epinephrine on the pre-anodized carbon paste electrode
Influence of acidity and auxiliary electrode reaction on the oxidation of epinephrine on the pre-anodized carbon paste electrode
复制标题
酸度和辅助电极反应对预阳极氧化碳糊电极上肾上腺素氧化的影响
DOI：
10.1016/j.electacta.2015.10.142
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发表时间：
2015-12
影响因子：
6.6
通讯作者：
Haijiang Wang
中科院分区：
文献类型：
--
作者：
Fengli Gao;Quanmin Li;Xiao-Zi Yuan;Haijiang Wang
本文研究了在“U”形电解槽中预阳极碳糊电极上，溶液酸度和辅助电极反应对肾上腺素氧化峰电流的影响机理。通过改变辅助电极电解槽(AEEC)和工作电极电解槽(WREEC)的溶液酸度，用循环伏安法研究了EP在WREEC中的电化学行为。结果表明，无论是WREEC还是AEEC，EP氧化峰电流的大小都与溶液的酸度密切相关。探讨了支持电解液、辅助电极上的还原反应、EP物种的分布和EP的分子构型对EP氧化峰电流的影响。此外，还提出并解释了阴极和阳极的反应机理。根据所提供的电极反应机理，可以根据分配系数选择最优的pH值，为以后的相关研究提供依据。应用这些机理对注射用EP进行测定，取得了满意的结果。
In this paper, the influence mechanisms of the solution acidity and the auxiliary electrode reaction on the oxidation peak current of epinephrine (EP) were researched on a pre-anodized carbon paste electrode in a “U” shape electrolytic cell. By changing the solution acidity in the auxiliary electrode electrolytic cell (AEEC) or the working electrode electrolytic cell (WREEC), the electrochemical behaviors of EP in the WREEC was investigated by cyclic voltammetry. It is found that the magnitude of the oxidation peak current of EP is closely related to the solution acidity for both WREEC and AEEC. The effects of the supporting electrolyte, the reduction reaction at the auxiliary electrode, distribution of the EP species and the molecular configuration of EP on the oxidation peak current of EP were also explored. Furthermore, the reaction mechanisms for both cathode and anode were proposed and interpreted. With the provided electrode reaction mechanisms, optimized pH value can be chosen based on the distribution coefficients for future related researches. Satisfactory results have been achieved for the determination of EP in injection using these mechanisms.
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影响因子：
6.6
作者：
J. Silva;Helena C. Junqueira;T. L. Ferreira
通讯作者：
J. Silva;Helena C. Junqueira;T. L. Ferreira
影响因子：
6.6
作者：
A. Pahlavan;V. Gupta;Afsaneh L. Sanati;F. Karimi;Mehdi Yoosefian;Mojtaba Ghadami
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影响因子：
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通讯作者：
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影响因子：
5.4
作者：
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通讯作者：
M. Ghalkhani;S. Shahrokhian
影响因子：
15
作者：
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通讯作者：
R. J. Klingler;J. Kochi