Evidence for the use of an internal sense of direction in homing.

Evidence for the use of an internal sense of direction in homing.
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在归航过程中使用内部方向感的证据。

DOI:
10.1037/a0018446
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发表时间:
2010
影响因子:
1.9
通讯作者:
Van Der Meer MAA
Van Der Meer MAA
中科院分区:
医学4区
文献类型:
--
作者:
Van Der Meer MAA

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路径整合是一种基于内部线索保持位置和方向表征的能力,被认为对导航和空间关系的学习很重要。大脑中的位置和方向的表征,如边缘系统中的头部方向细胞、网格细胞和位置细胞,被认为是通过路径整合进行导航的基础。虽然这一想法通常与病变研究一致,但尚未在动物明显使用路径整合策略的任务中研究过这种神经活动和行为之间的关系。在这里,我们报告了这样一个任务在大鼠中的发展:通过缓慢旋转大鼠之前,他们返回到一个试验独特的家庭基地,我们可以显示受试者依赖于内部线索只导航。为了说明如何将这项任务与记录相结合,我们展示了同时记录的头部方向细胞的例子,其中神经活动与大鼠的归巢方向密切相关。这些结果支持的概念,大鼠可以通过路径整合导航,这种能力取决于头部方向细胞,并建议一个方便的行为范式调查导航的神经基础。(PsycInfo数据库记录(c)2016阿帕,保留所有权利)
Path integration, the ability to maintain a representation of location and direction on the basis of internal cues, is thought to be important for navigation and the learning of spatial relationships. Representations of location and direction in the brain, such as head direction cells, grid cells, and place cells in the limbic system, are thought to underlie navigation by path integration. While this idea is generally consistent with lesion studies, the relationship between such neural activity and behavior has not been studied on a task where animals demonstrably use a path integration strategy. Here we report the development of such a task in rats: by slowly rotating rats before their return to a trial-unique home base, we could show subjects relied on internal cues only to navigate. To illustrate how this task can be combined with recording, we show examples of simultaneously recorded head direction cells in which neural activity is closely related to rats’ homing direction. These results support the notion that rats can navigate by path integration, that this ability depends on head direction cells, and suggest a convenient behavioral paradigm for investigating the neural basis of navigation.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
DOI: 10.1016/s0003-3472(86)80054-9
发表时间: 1986-06-01
期刊: ANIMAL BEHAVIOUR
影响因子: 2.5
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影响因子: 2.5
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