Neural processing of gustatory information in insular circuits.

Neural processing of gustatory information in insular circuits.
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DOI:
10.1016/j.conb.2012.04.001
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发表时间:
2012-08
影响因子:
5.7
通讯作者:
Fontanini A
Fontanini A
中科院分区:
医学2区
文献类型:
--
作者:
Maffei A;Haley M;Fontanini A

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岛叶皮质是负责味觉处理的主要皮质部位。有大量的证据表明,在麻醉和正常活动的动物中,岛状神经元是如何对味觉刺激作出反应的。大多数报告描述了广泛调谐的神经元,这些神经元参与处理味觉体验的化学感觉、生理和心理方面。然而,人们对这些神经反应如何映射到岛岛回路知之甚少。特别神秘的是岛叶皮层的三个分支的功能作用:颗粒状、非颗粒状和颗粒状岛叶皮层。在这篇文章中,我们回顾了本地和长途电路在三个分支机构的组织数据。结合最新的电生理数据,讨论了这些结果的功能意义。岛叶皮层是一个功能完整的系统,致力于处理味觉、多模态、认知和情感信息。
The insular cortex is the primary cortical site devoted to taste processing. A large body of evidence is available for how insular neurons respond to gustatory stimulation in both anesthetized and behaving animals. Most of the reports describe broadly tuned neurons that are involved in processing the chemosensory, physiological and psychological aspects of gustatory experience. However little is known about how these neural responses map onto insular circuits. Particularly mysterious is the functional role of the three subdivisions of the insular cortex: the granular, the dysgranular and the agranular insular cortices. In this article we review data on the organization of the local and long-distance circuits in the three subdivisions. The functional significance of these results is discussed in light of the latest electrophysiological data. A view of the insular cortex as a functionally integrated system devoted to processing gustatory, multimodal, cognitive and affective information is proposed.
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