Artificial sweeteners: a systematic review of metabolic effects in youth.
Artificial sweeteners: a systematic review of metabolic effects in youth.
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DOI：
10.3109/17477160903497027
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发表时间：
2010-08
期刊：
影响因子：
--
通讯作者：
Rother KI
中科院分区：
文献类型：
--
作者：
Brown RJ;de Banate MA;Rother KI
流行病学数据表明，人工甜味剂的使用与体重增加之间存在关联。人造甜味剂的使用与体重增加和其他代谢健康影响之间存在因果关系的证据有限。然而，最近的动物研究提供了有趣的信息，支持人工甜味剂的活跃代谢作用。本系统综述研究了有关儿童人造甜味剂消费及其健康影响的最新文献。确定了十八项研究。大型流行病学研究的数据支持人工加糖饮料的消费与儿童体重增加之间存在关联。儿童随机对照试验非常有限，并且没有明确证明人工甜味剂对代谢的有益或不利影响。目前，还没有强有力的临床证据证明人工甜味剂的使用和代谢健康影响之间存在因果关系，但重要的是检查这些常见食品添加剂对全球儿童肥胖和糖尿病上升的可能贡献。
Epidemiological data have demonstrated an association between artificial sweetener use and weight gain. Evidence of a causal relationship linking artificial sweetener use to weight gain and other metabolic health effects is limited. However, recent animal studies provide intriguing information that supports an active metabolic role of artificial sweeteners. This systematic review examines the current literature on artificial sweetener consumption in children and its health effects. Eighteen studies were identified. Data from large, epidemiologic studies support the existence of an association between artificially-sweetened beverage consumption and weight gain in children. Randomized controlled trials in children are very limited, and do not clearly demonstrate either beneficial or adverse metabolic effects of artificial sweeteners. Presently, there is no strong clinical evidence for causality regarding artificial sweetener use and metabolic health effects, but it is important to examine possible contributions of these common food additives to the global rise in pediatric obesity and diabetes.
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影响因子：
16.2
作者：
Brown RJ;Walter M;Rother KI
通讯作者：
Rother KI
影响因子：
5.4
作者：
Bellissimo, Nick;Thomas, Scott G.;Anderson, G. Harvey
通讯作者：
Anderson, G. Harvey
条件性和非条件性热量补偿--幼儿食物摄入量自我调节的证据
影响因子：
1.4
作者：
BIRCH, LL;DEYSHER, M
通讯作者：
DEYSHER, M
DOI：
10.1080/07315724.2005.10719449
发表时间：
2005-04-01
影响因子：
3.5
作者：
Blum, JW;Jacobsen, DJ;Donnelly, JE
通讯作者：
Donnelly, JE
影响因子：
8
作者：
Ebbeling, CB;Feldman, HA;Ludwig, DS
通讯作者：
Ludwig, DS