Immunohistochemical localization of prostaglandin endoperoxide synthase in human fetal membranes and decidua.

Immunohistochemical localization of prostaglandin endoperoxide synthase in human fetal membranes and decidua.
复制标题

人胎膜和蜕膜中前列腺素内过氧化物合酶的免疫组织化学定位。

DOI:
10.1095/biolreprod41.4.701
复制
发表时间:
1989
影响因子:
3.6
通讯作者:
Clark,MR
Clark,MR
中科院分区:
生物学2区
文献类型:
--
作者:
Price,TM;Kauma,SW;CurryJr,TE;Clark,MR

文献摘要

参考文献

被引文献

相似文献

前列腺素在妊娠维持和分娩启动过程中起重要作用。前列腺素内过氧化物合酶活性已在人胎膜和蜕膜中得到证实。使用免疫组织化学技术,我们确定在这些组织中的细胞类型,含有前列腺素内过氧化物合酶。共33例标本,从8周至42周的妊娠,进行了研究。在所有细胞类型中,蜕膜基质细胞的染色最强烈且最一致。所有胎龄的绒毛膜和早期胎盘绒毛的细胞滋养层和合体滋养层显示出更浅、更多变的染色模式。无论胎龄如何,羊膜以异质方式染色,一些细胞显示出强烈的染色,而其他细胞没有染色。有没有观察到的差异,在劳动相比,nonlaboring长期标本。总之,已在胎膜和蜕膜中鉴定出含有免疫反应性前列腺素内过氧化物合酶的特定细胞类型。
Prostaglandins play an important role during the maintenance of pregnancy and the initiation of parturition. Prostaglandin endoperoxide synthase activity has been demonstrated in human fetal membranes and decidua. Using immunohistochemical techniques, we identified in these tissues the cell types that contain prostaglandin endoperoxide synthase. A total of 33 specimens, ranging from 8 wk to 42 wk gestation, were studied. Decidualized stromal cells stained the most intensely and consistently of all cell types. Cytotrophoblast of the chorion and early placental villi and syncytotrophoblast of all gestational ages demonstrated a lighter, more variable staining pattern. Regardless of gestational age, amnion stained in a heterogeneous fashion, with some cells demonstrating an intense staining and other cells having no staining. There were no observable differences in laboring compared to nonlaboring term specimens. In summary, the specific cell types that contain immunoreactive prostaglandin endoperoxide synthase have been identified in fetal membranes and decidua.
怀孕期间和围产期的前列腺素。
DOI: --
发表时间: 1981
期刊: Journal of Reproduction and Fertility
影响因子: --
作者:
M. Mitchell
通讯作者: M. Mitchell
内质网中前列腺素内过氧化物合酶的活性位点和抗原决定簇的方向。
DOI: --
发表时间: 1981
期刊: The Journal of biological chemistry
影响因子: --
作者:
DeWitt,DL;Rollins,TE;Day,JS;Gauger,JA;Smith,WL
通讯作者: Smith,WL
第 5 章 – 蛋白质从二维凝胶到片材的电泳转移及其检测
DOI: 10.1016/b978-0-12-164720-9.50009-x
发表时间: 1984
影响因子: 3.3
作者:
J. Symington
通讯作者: J. Symington
DOI: 10.1016/0002-9378(81)90312-4
发表时间: 1981-01-01
影响因子: 9.8
作者:
OKAZAKI, T;CASEY, ML;JOHNSTON, JM
通讯作者: JOHNSTON, JM
内源性抑制剂对牛胎盘前列腺素合成的调节。
DOI: --
发表时间: 1984
期刊: Endocrinology
影响因子: 4.8
作者:
M. Shemesh;W. Hansel;J. Strauss
通讯作者: J. Strauss