Sensitivity enhancement of a grating-based surface plasmon-coupled emission (SPCE) bionsor chip using gold thickness.
Sensitivity enhancement of a grating-based surface plasmon-coupled emission (SPCE) bionsor chip using gold thickness.
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DOI:
10.1016/j.cplett.2013.10.081
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发表时间:
2014-01-20
影响因子:
2.8
通讯作者:
Lynes, Michael A.
中科院分区:
文献类型:
--
作者:
Yuk, Jong Seol;Guignon, Ernest F.;Lynes, Michael A.
We describe a novel approach to enhance the sensitivity of a grating-based surface plasmon-coupled emission (SPCE) sensor by increasing the thickness of the metal film used in this system. The calculated optical properties of grating-based SPR spectra were significantly affected by both grating depth and by gold thickness. Higher angular sensitivity could be achieved at short wavelengths and under in situ measurement (analysis under aqueous condition). We confirmed the predicated enhancements of SPCE response using Alexa Fluor 647-labeled anti-mouse IgG immobilized on the SPCE sensor chips. Grating-coupled SPCE sensor chips can be used as a useful tool for high contents analysis of chemical and biomolecular interactions.
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影响因子:
4.3
作者:
Yuk, Jong Seol;McDonagh, Colette;MacCraith, Brian D.
通讯作者:
MacCraith, Brian D.
影响因子:
6.2
作者:
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DOI:
10.1016/j.bbrc.2003.12.010
发表时间:
2004-01-16
影响因子:
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作者:
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通讯作者:
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影响因子:
4.2
作者:
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通讯作者:
Lynes, Michael A.
影响因子:
12.6
作者:
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通讯作者:
Lynes, Michael A.