Case Report: Acute Spinal Cord Myelopathy in Patients With COVID-19.
Case Report: Acute Spinal Cord Myelopathy in Patients With COVID-19.
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DOI：
10.3389/fneur.2020.610648
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发表时间：
2020
影响因子：
3.4
通讯作者：
Soliman RK
中科院分区：
文献类型：
--
作者：
Khedr EM;Karim AA;Soliman RK
COVID-19通常与发热和严重呼吸道症状（包括干咳和呼吸困难）相关。然而，COVID-19也可能影响中枢和外周神经系统。迄今为止，COVID-19脊髓受累的发病率尚不清楚，发病机制仍未完全了解。我们在这里报告了2020年7月1日至8月10日期间在艾斯尤特大学医院/埃及住院的两名女性患者。两人的鼻咽拭子SARS-CoV-2聚合酶链反应（PCR）均呈阳性，血清d-二聚体和铁蛋白水平升高，CT胸部扫描显示双侧毛玻璃样外观。第一位是一位60岁的女性，在流感样症状后10天急性发作弛缓性截瘫，MRI显示横肌萎缩。第二例患者为21岁女性，症状为急性四肢瘫痪、发热、头痛和嗅觉丧失，MRI扫描显示长颈胸脊髓病。脊髓前动脉闭塞和可能的横肌萎缩被认为是长节段脊髓病的鉴别诊断。
COVID-19 is typically associated with fever and severe respiratory symptoms including dry cough and dyspnea. However, COVID-19 may also affect both central and peripheral nervous systems. To date, the incidence rate of spinal cord involvement in COVID-19 is not known and the pathogenesis is still not fully understood. We report here two female patients admitted to Assiut University Hospitals/Egypt during the period from first of July to August 10, 2020. Both presented with a positive SARS-CoV-2 polymerase chain reaction (PCR) nasopharyngeal swab, elevated serum d-dimer and ferritin levels, and bilateral ground glass appearance in a CT chest scan. The first was a 60-year-old female with acute onset of flaccid paraplegia 10 days after flu-like symptoms, in whom MRI revealed transverse myelitis. The second was a 21-year-old female with symptoms of acute quadriplegia, fever, headache, and anosmia in whom an MRI scan revealed long cervico-thoracic myelopathy. Anterior spinal artery occlusion and possibly transverse myelitis were considered as differential diagnosis of long segment myelopathy.
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影响因子：
5.9
作者：
Swanson, Phillip A., II;McGavern, Dorian B.
通讯作者：
McGavern, Dorian B.
DOI：
10.5811/cpcem.2020.5.47937
发表时间：
2020-08-01
影响因子：
--
作者：
Sarma, Deesha;Bilello, Leslie A
通讯作者：
Bilello, Leslie A
影响因子：
--
作者：
Desforges M;Le Coupanec A;Brison E;Meessen-Pinard M;Talbot PJ
通讯作者：
Talbot PJ
影响因子：
9.9
作者：
Greenberg, B. M.;Thomas, K. P.;Kerr, D. A.
通讯作者：
Kerr, D. A.
影响因子：
5.3
作者：
Awad A;Stüve O
通讯作者：
Stüve O