Anterior pituitary, adrenal, and gonadal hormones during cocaine withdrawal.

Anterior pituitary, adrenal, and gonadal hormones during cocaine withdrawal.
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可卡因戒断期间的垂体前叶、肾上腺和性腺激素。

DOI:
10.1176/ajp.145.9.1094
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发表时间:
1988
期刊:
The American journal of psychiatry
影响因子:
--
通讯作者:
Ellingboe,J
Ellingboe,J
中科院分区:
--
文献类型:
--
作者:
Mendelson,JH;Teoh,SK;Lange,U;Mello,NK;Weiss,R;Skupny,A;Ellingboe,J

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Plasma luteinizing hormone (LH), prolactin, testosterone, and cortisol levels were determined in 16 patients after hospital admission for cocaine abuse, during the course of 4 weeks of hospitalization, and before discharge. Hyperprolactinemia was found at admission (mean +/- SD, 27.5 +/- 10.2 ng/ml) and persisted until discharge (mean +/- SD, 28.7 +/- 10.8 ng/ml). Plasma LH, testosterone, and cortisol levels were within normal limits. These findings suggest that persistent elevation of plasma prolactin levels after cocaine withdrawal may reflect a chronic cocaine-induced derangement in neural dopaminergic regulatory systems.
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