Psychobiological operationalization of RDoC constructs: Methodological and conceptual opportunities and challenges.
Psychobiological operationalization of RDoC constructs: Methodological and conceptual opportunities and challenges.
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RDoC 结构的心理生物学操作化：方法论和概念上的机遇和挑战。
DOI：
10.1111/psyp.12587
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发表时间：
2016
期刊：
影响因子：
3.7
通讯作者：
Phan,KLuan
中科院分区：
文献类型：
--
作者：
MacNamara,Annmarie;Phan,KLuan
NIMH的研究领域标准（RDoC）项目旨在通过促进对维度结构的心理生物学研究来推进精神障碍的诊断、预防和治疗，这些维度结构可能会跨越传统的诊断界限（Kozak & Cuthbert,）。这种方法的核心概念是，这些维度结构可以跨不同的分析单位（例如，基因、生理、行为）进行评估，从而丰富结构并为临床问题提供更完整的解释。虽然在之前的几篇论文中已经讨论了RDoC的概念方面，但其方法方面受到的关注相对较少。例如，如何整合来自不同分析单元的数据一直相对不清楚。在这里，我们讨论了跨不同分析单元的心理生物学操作化RDoC结构的一种方法（心理神经测量方法；Yancey等人），强调了该方法在未来迭代中可能被改进的方法。我们的结论是，从这种技术中可以学到很多东西；然而，对量表开发方法和心理测量学的更多关注可能会使这种方法和其他方法受益，从而将多个分析单元的测量结合起来。
NIMH's Research Domain Criteria (RDoC) project seeks to advance the diagnosis, prevention, and treatment of mental disorders by promoting psychobiological research on dimensional constructs that might cut across traditional diagnostic boundaries (Kozak & Cuthbert, ). At the core of this approach is the notion that these dimensional constructs can be assessed across different units of analysis (e.g., genes, physiology, behavior), enriching the constructs and providing more complete explanations of clinical problems. While the conceptual aspects of RDoC have been discussed in several prior papers, its methodological aspects have received comparatively less attention. For example, how to integrate data from different units of analysis has been relatively unclear. Here, we discuss one means of psychobiologically operationalizing RDoC constructs across different units of analysis (the psychoneurometric approach; Yancey et al., ), highlighting ways in which this approach might be refined in future iterations. We conclude that there is much to be learned from this technique; however, greater attention to scale‐development methods and to psychometrics will likely benefit this and other methodological approaches to combining measurements across multiple units of analysis.
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