Outer retinal thickness and visibility of the choriocapillaris in four distinct retinal regions imaged with spectral domain optical coherence tomography in dogs and cats.
Outer retinal thickness and visibility of the choriocapillaris in four distinct retinal regions imaged with spectral domain optical coherence tomography in dogs and cats.
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DOI：
10.1111/vop.12989
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发表时间：
2022-05
影响因子：
1.6
通讯作者：
Pot, Simon A.
中科院分区：
文献类型：
--
作者：
Mischi, Elisa;Soukup, Petr;Harman, Christine D.;Oikawa, Kazuya;Kowalska, Malwina E.;Hartnack, Sonja;McLellan, Gillian J.;Komaromy, Andras M.;Pot, Simon A.
评价使用光谱域光学相干断层扫描（SD‐OCT）成像的犬和猫4个不同视网膜区域的外视网膜带厚度和脉络膜毛细血管（CC）可见性。通过识别视网膜区域之间的外视网膜厚度差异，尝试在犬和猫SD‐OCT扫描中描绘中央凹样区域。分析了健康麻醉犬（n = 10）和猫（n = 12）的Spectralis® HRA + OCT SD‐OCT扫描。对CC可识别的扫描线进行计数，并对CC可见性进行评分。在中央区域（AC）（视觉识别的中心凹样区域）以及视神经乳头（ONH）的上级和下级区域中测量外核层（ONL）厚度以及从外界膜（ELM）到视网膜色素上皮/布鲁赫膜复合体（RPE/BM）以及从ELM到CC的距离。使用多水平回归分析测量结果。CC在狗和猫的90%以上的扫描线中可见。ONL在中央凹样区域始终最薄。在犬和猫中，与上级和低级ONH相比，AC内的外视网膜（ELM-RPE和ELM-CC）最厚（所有比较p <0.001）。CC似乎是一个有效的，虽然不太理想的外部视网膜边界标记绒毡层物种。在犬和猫的SD-OCT图像上，AC可以与周围视网膜客观区分;在犬中发现了一个中央凹样区域，并提示猫中存在该区域。这些发现允许对视网膜特化的这些区域进行靶向成像和图像评估。
To evaluate the outer retinal band thickness and choriocapillaris (CC) visibility in four distinct retinal regions in dogs and cats imaged with spectral domain optical coherence tomography (SD‐OCT). To attempt delineation of a fovea‐like region in canine and feline SD‐OCT scans, aided by the identification of outer retinal thickness differences between retinal regions. Spectralis® HRA + OCT SD‐OCT scans from healthy, anesthetized dogs (n = 10) and cats (n = 12) were analyzed. Scanlines on which the CC was identifiable were counted and CC visibility was scored. Outer nuclear layer (ONL) thickness and the distances from external limiting membrane (ELM) to retinal pigment epithelium/Bruch's membrane complex (RPE/BM) and ELM to CC were measured in the area centralis (AC), a visually identified fovea‐like region, and in regions superior and inferior to the optic nerve head (ONH). Measurements were analyzed using a multilevel regression. The CC was visible in over 90% of scanlines from dogs and cats. The ONL was consistently thinnest in the fovea‐like region. The outer retina (ELM‐RPE and ELM‐CC) was thickest within the AC compared with superior and inferior to the ONH in dogs and cats (p < .001 for all comparisons). The CC appears a valid, albeit less than ideal outer retinal boundary marker in tapetal species. The AC can be objectively differentiated from the surrounding retina on SD‐OCT images of dogs and cats; a fovea‐like region was identified in dogs and its presence was suggested in cats. These findings allow targeted imaging and image evaluation of these regions of retinal specialization.
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影响因子：
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作者：
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通讯作者：
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