State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes.
State-dependent judgement bias in Drosophila: evidence for evolutionarily primitive affective processes.
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DOI:
10.1098/rsbl.2017.0779
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发表时间:
2018-03
期刊:
影响因子:
3.3
通讯作者:
Hodge JJL
中科院分区:
文献类型:
--
作者:
Deakin A;Mendl M;Browne WJ;Paul ES;Hodge JJL
Affective states influence decision-making under ambiguity in humans and other animals. Individuals in a negative state tend to interpret ambiguous cues more negatively than individuals in a positive state. We demonstrate that the fruit fly, Drosophila melanogaster, also exhibits state-dependent changes in cue interpretation. Drosophila were trained on a Go/Go task to approach a positive (P) odour associated with a sugar reward and actively avoid a negative (N) odour associated with shock. Trained flies were then either shaken to induce a purported negative state or left undisturbed (control), and given a choice between: air or P; air or N; air or ambiguous odour (1 : 1 blend of P : N). Shaken flies were significantly less likely to approach the ambiguous odour than control flies. This ‘judgement bias’ may be mediated by changes in neural activity that reflect evolutionarily primitive affective states. We cannot say whether such states are consciously experienced, but use of this model organism's versatile experimental tool kit may facilitate elucidation of their neural and genetic basis.
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DOI:
10.1007/bf00611923
发表时间:
1978-01-01
期刊:
JOURNAL OF COMPARATIVE PHYSIOLOGY
影响因子:
--
作者:
BICKER, G;REICHERT, H
通讯作者:
REICHERT, H
影响因子:
4.6
作者:
Barekat A;Gonzalez A;Mauntz RE;Kotzebue RW;Molina B;El-Mecharrafie N;Conner CJ;Garza S;Melkani GC;Joiner WJ;Lipinski MM;Finley KD;Ratliff EP
通讯作者:
Ratliff EP
影响因子:
64.5
作者:
Anderson DJ;Adolphs R
通讯作者:
Adolphs R
影响因子:
2.3
作者:
Mendl, Michael;Burman, Oliver H. P.;Paul, Elizabeth S.
通讯作者:
Paul, Elizabeth S.
影响因子:
5.3
作者:
Schwaerzel, M;Monastirioti, M;Heisenberg, M
通讯作者:
Heisenberg, M