The role of absolute humidity in respiratory mortality in Guangzhou, a hot and wet city of South China.
The role of absolute humidity in respiratory mortality in Guangzhou, a hot and wet city of South China.
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DOI：
10.1186/s12199-021-01030-3
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发表时间：
2021-11-17
影响因子：
4.7
通讯作者：
Xiong K
中科院分区：
文献类型：
--
作者：
Chen S;Liu C;Lin G;Hänninen O;Dong H;Xiong K
中国，由于许多研究对湿度对呼吸系统疾病的影响没有定论，我们考察了绝对湿度与呼吸系统疾病死亡率的关系，并量化了广州地区由于非最佳绝对湿度造成的死亡负担。收集广州市2013年2月1日至2018年12月31日呼吸系统疾病日死亡人数42440人及同期气象资料。利用分布滞后非线性模型确定了最优死亡绝对湿度，并讨论了其非线性滞后效应。根据最优绝对湿度(定义为最小死亡率绝对湿度)计算归因分数和人口归因死亡率。绝对湿度与呼吸系统疾病总死亡率之间的关系呈M型非线性曲线。总体而言，21.57%(95%可信区间14.20~27.75%)的呼吸系统疾病死亡(9154例死亡)可归因于非最佳绝对湿度。高绝对湿度的归因率为13.49%(95%CI 9.56~16.98%)，低绝对湿度的死亡负担为8.08%(95%CI 0.89~13.93%)。极端干燥和潮湿的绝对湿度分别占呼吸系统疾病总死亡率的0.87%(95%CI−0.09~1.58%)和0.91%(95%CI 0.25~1.39%)。绝对湿度造成的归因风险负担没有显著的性别和年龄差异。我们的研究表明，高绝对湿度和低绝对湿度都是造成相当大的呼吸系统疾病死亡负担的原因，归因于高绝对湿度的分量影响更大。我们的结果可能对制定公共卫生措施以降低呼吸道疾病死亡率具有重要意义。网上版载有补充材料，可在10.1186/s12199-021-01030-3查阅。
For the reason that many studies have been inconclusive on the effect of humidity on respiratory disease, we examined the association between absolute humidity and respiratory disease mortality and quantified the mortality burden due to non-optimal absolute humidity in Guangzhou, China. Daily respiratory disease mortality including total 42,440 deaths from 1 February 2013 to 31 December 2018 and meteorological data of the same period in Guangzhou City were collected. The distributed lag non-linear model was used to determine the optimal absolute humidity of death and discuss their non-linear lagged effects. Attributable fraction and population attributable mortality were calculated based on the optimal absolute humidity, defined as the minimum mortality absolute humidity. The association between absolute humidity and total respiratory disease mortality showed an M-shaped non-linear curve. In total, 21.57% (95% CI 14.20 ~ 27.75%) of respiratory disease mortality (9154 deaths) was attributable to non-optimum absolute humidity. The attributable fractions due to high absolute humidity were 13.49% (95% CI 9.56 ~ 16.98%), while mortality burden of low absolute humidity were 8.08% (95% CI 0.89 ~ 13.93%), respectively. Extreme dry and moist absolute humidity accounted for total respiratory disease mortality fraction of 0.87% (95% CI − 0.09 ~ 1.58%) and 0.91% (95% CI 0.25 ~ 1.39%), respectively. There was no significant gender and age difference in the burden of attributable risk due to absolute humidity. Our study showed that both high and low absolute humidity are responsible for considerable respiratory disease mortality burden, the component attributed to the high absolute humidity effect is greater. Our results may have important implications for the development of public health measures to reduce respiratory disease mortality. The online version contains supplementary material available at 10.1186/s12199-021-01030-3.
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影响因子：
5
作者：
Barreca, Alan I.;Shimshack, Jay P.
通讯作者：
Shimshack, Jay P.
影响因子：
3.8
作者：
Pham Quang Thai;Choisy, Marc;Horby, Peter
通讯作者：
Horby, Peter
DOI：
10.1016/s0140-6736(14)62114-0
发表时间：
2015-07-25
期刊：
Lancet (London, England)
影响因子：
--
作者：
Gasparrini A;Guo Y;Hashizume M;Lavigne E;Zanobetti A;Schwartz J;Tobias A;Tong S;Rocklöv J;Forsberg B;Leone M;De Sario M;Bell ML;Guo YL;Wu CF;Kan H;Yi SM;de Sousa Zanotti Stagliorio Coelho M;Saldiva PH;Honda Y;Kim H;Armstrong B
通讯作者：
Armstrong B
影响因子：
10.4
作者：
Mendell MJ;Mirer AG;Cheung K;Tong M;Douwes J
通讯作者：
Douwes J
影响因子：
9.8
作者：
Leitte, Arne Marian;Petrescu, Cristina;Schlink, Uwe
通讯作者：
Schlink, Uwe