MRI-defined paraspinal muscle morphology in Japanese population: The Wakayama Spine Study.
MRI-defined paraspinal muscle morphology in Japanese population: The Wakayama Spine Study.
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DOI：
10.1371/journal.pone.0187765
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发表时间：
2017
期刊：
影响因子：
3.7
通讯作者：
Yoshida M
中科院分区：
文献类型：
--
作者：
Sasaki T;Yoshimura N;Hashizume H;Yamada H;Oka H;Matsudaira K;Iwahashi H;Shinto K;Ishimoto Y;Nagata K;Teraguchi M;Kagotani R;Muraki S;Akune T;Tanaka S;Kawaguchi H;Nakamura K;Minamide A;Nakagawa Y;Yoshida M
本研究旨在建立椎旁肌横截面积和脂肪浸润率的性别和年龄依赖性分布，并研究日本人群中椎旁肌变性与腰痛之间的相关性。在这项横断面研究中，分析了 796 名参与者（241 名男性，555 名女性；平均年龄 63.5 岁）的数据。使用轴向T2加权磁共振成像测量T12/L1至L4/5水平的竖脊肌和多裂肌以及T12/L1水平的腰大肌的横截面积和脂肪浸润率。使用多变量逻辑回归分析来估计椎旁肌肉的脂肪浸润与腰痛患病率之间的关联。男性的横截面积大于女性，并且随着年龄的增长而趋于减小，但女性 T12/L1 和 L1/2 处的竖脊肌除外。除70~79岁T12/L1多裂肌和50岁以下腰大肌外，男性脂肪浸润率低于女性，且随年龄增长呈增加趋势。调整年龄、性别和体重指数后的Logistic回归分析显示，L1/2和L2/3处竖脊肌的脂肪浸润率与腰痛显着相关（L1/2水平：比值比，1.05；95%置信区间，1.005-1.104；L2/3水平：比值比，1.05；95%置信区间， 1.001–1.113）。这项研究利用磁共振成像测量了日本人群椎旁肌的横截面积和脂肪浸润率，并证明上腰椎竖脊肌的脂肪浸润率与腰痛的存在显着相关。测量结果可以用作参考值，这对于未来的比较研究很重要。
This study aimed to establish sex- and age-dependent distributions of the cross sectional area and fatty infiltration ratio of paraspinal muscles, and to examine the correlation between paraspinal muscle degeneration and low back pain in the Japanese population. In this cross-sectional study, data from 796 participants (241 men, 555 women; mean age, 63.5 years) were analyzed. The measurement of the cross sectional area and fatty infiltration ratio of the erector spinae and multifidus from the level of T12/L1 to L4/5 and psoas major at the level of T12/L1 was performed using axial T2-weighted magnetic resonance imaging. Multivariate logistic regression analysis was used to estimate the association between fatty infiltration of the paraspinal muscles and the prevalence of low back pain. The cross sectional area was larger in men than women, and tended to decrease with age, with the exception of the erector spinae at T12/L1 and L1/2 in women. The fatty infiltration ratio was lower in men than women, except for multifidus at T12/L1 in 70–79 year-olds and psoas major in those less than 50 years-old, and tended to increase with age. Logistic regression analysis adjusted for age, sex, and body mass index showed that the fatty infiltration ratio of the erector spinae at L1/2 and L2/3 was significantly associated with low back pain (L1/2 level: odds ratio, 1.05; 95% confidence interval, 1.005–1.104; L2/3 level: odds ratio, 1.05; 95% confidence interval, 1.001–1.113). This study measured the cross sectional area and fatty infiltration ratio of paraspinal muscles in the Japanese population using magnetic resonance imaging, and demonstrated that the fatty infiltration ratio of the erector spinae in the upper lumbar spine was significantly associated with the presence of low back pain. The measurements could be used as reference values, which are important for future comparative studies.
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影响因子：
3.5
作者：
Crawford, R. J.;Filli, L.;Ulbrich, E. J.
通讯作者：
Ulbrich, E. J.
DOI：
10.1067/mlc.2001.113504
发表时间：
2001-04-01
期刊：
JOURNAL OF LABORATORY AND CLINICAL MEDICINE
影响因子：
--
作者：
Morley, JE;Baumgartner, RN;Nair, KS
通讯作者：
Nair, KS
影响因子：
5.3
作者：
Marzetti E;Carter CS;Wohlgemuth SE;Lees HA;Giovannini S;Anderson B;Quinn LS;Leeuwenburgh C
通讯作者：
Leeuwenburgh C
影响因子：
7.4
作者：
Macfarlane, Gary J.;Beasley, Marcus;Jones, Gareth T.
通讯作者：
Jones, Gareth T.
影响因子：
3.5
作者：
Ali S;Garcia JM
通讯作者：
Garcia JM