Racial/ethnic and neighborhood disparities in metals exposure during pregnancy in the Northeastern United States.

Racial/ethnic and neighborhood disparities in metals exposure during pregnancy in the Northeastern United States.
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DOI:
10.1016/j.scitotenv.2022.153249
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发表时间:
2022-05-10
期刊:
The Science of the total environment
影响因子:
--
通讯作者:
Wright RJ
Wright RJ
中科院分区:
其他
文献类型:
--
作者:
Geron M;Cowell W;Amarasiriwardena C;Andra SS;Carroll K;Kloog I;Wright RO;Wright RJ

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尽管少数种族社区承受的环境暴露负担不平等,但这些群体在公共卫生研究中的代表性往往不足。在这里,我们研究了种族/民族的差异,暴露于金属之间的多民族样本的孕妇。我们的目标是研究什么样的差异,如果有的话,存在于孕妇的样本中的金属暴露。样本包括参加代际压力机制(PRISM)妊娠队列的女性(N = 382)。尿金属浓度(砷[As],钡[Ba],镉[Cd],铯[Cs],铬[Cr],铅[Pb],锑[Sb])进行了测量,在怀孕中期和个人和邻里水平的特征的信息进行了确定,在一个人的访谈和公开的数据库,分别。线性回归被用来检查个人和邻里的特点,金属浓度。黑人/黑人-西班牙裔女性的镉、铬、铅和锑水平分别比白色、非西班牙裔女性高142.0%、10.9%、35.0%和32.1%。同样,西班牙裔白人女性的相应水平分别高出141.5%、108.2%、59.9%和38.3%。在犯罪率较高、多样性较高、教育程度较低、家庭收入较低和贫困程度较高的地区,这些金属含量也较高。在接触金属方面存在着显著差异,可能是由社区一级的因素驱动的。孕妇接触金属可能特别有害。了解暴露不平等和确定增加风险的因素有助于为有针对性的公共卫生干预提供信息。将与任何后续修订一起提供。
Despite the unequal burden of environmental exposures borne by racially minoritized communities, these groups are often underrepresented in public health research. Here, we examined racial/ethnic disparities in exposure to metals among a multi-ethnic sample of pregnant women. Our objective was to examine what disparities, if any, exist in metal exposure among a sample of pregnant women. The sample included women enrolled in the PRogramming of Intergenerational Stress Mechanisms (PRISM) pregnancy cohort (N = 382). Urinary metal concentrations (arsenic [As], barium [Ba], cadmium [Cd], cesium [Cs], chromium [Cr], lead [Pb], antimony [Sb]) were measured during mid-pregnancy and information on individual- and neighborhood-level characteristics was ascertained during an in-person interview and from publicly available databases, respectively. Linear regression was used to examine individual and neighborhood characteristics in relation to metal concentrations. Black/Black-Hispanic women had Cd, Cr, Pb, and Sb levels that were 142.0%, 10.9%, 35.0%, and 32.1% higher than White, non-Hispanic women, respectively. Likewise, White-Hispanic women had corresponding levels that were 141.5%, 108.2%, 59.9%, and 38.3% higher. These same metals were also higher among women residing in areas with higher crime, higher diversity, lower educational attainment, lower household income, and higher poverty. Significant disparities in exposure to metals exist and may be driven by neighborhood-level factors. Exposure to metals for pregnant women can be especially harmful. Understanding exposure inequalities and identifying factors that increase risk can help inform targeted public health interventions. To be supplied with any subsequent revisions.
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