Effects of sequential fluoxetine and gender on prequit depressive symptoms, affect, craving, and quit day abstinence in smokers with elevated depressive symptoms: a growth curve modeling approach.
Effects of sequential fluoxetine and gender on prequit depressive symptoms, affect, craving, and quit day abstinence in smokers with elevated depressive symptoms: a growth curve modeling approach.
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序贯氟西汀和性别对抑郁症状加重的吸烟者戒烟前抑郁症状、情感、渴望和戒烟日戒断的影响：生长曲线建模方法。
DOI：
10.1037/a0037156
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发表时间：
2014
影响因子：
2.3
通讯作者：
Brown,RichardA
中科院分区：
文献类型：
--
作者：
Minami,Haruka;Kahler,ChristopherW;Bloom,ErikaLitvin;Prince,MarkA;Abrantes,AnaM;Strong,DavidR;Niaura,Raymond;Miller,IvanW;PalmReed,KathleenM;Price,LawrenceH;Brown,RichardA
Although the important roles of postquit affect and withdrawal symptoms in the process of smoking cessation have been well established, little is known about the relations between prequit affective trajectories and cessation outcome on the target quit date (TQD). This study examined whether a 16-week course of fluoxetine initiated 8 weeks prequit (“sequential” fluoxetine) improved TQD abstinence relative to placebo through its effects on prequit depressive symptoms, affect (withdrawal-relevant negative affect, general negative affect, and positive affect), and craving to smoke among 206 smokers with elevated depressed symptoms. The moderating effects of gender were also examined. In total, 83 smokers (40%) failed to achieve abstinence on TQD, with no difference between treatment conditions or gender. Overall structural equation models showed that fluoxetine had significant indirect effects on TQD abstinence through changes in prequit withdrawal-relevant negative affect and craving, but not depressive symptoms. However, multigroup analyses revealed gender differences. Sequential fluoxetine reduced prequit depressive symptoms, withdrawal-relevant negative affect, and craving only among women. Reduction in prequit depressive symptoms and craving among women, and withdrawal-relevant negative affect among men was associated with TQD abstinence. Moreover, exploratory analysis showed negative trend-level indirect effects of fluoxetine on TQD abstinence via increased side effects, regardless of gender. This study demonstrated the importance of considering gender when examining treatment efficacy. Identifying ways to further reduce prequit depressive symptoms and craving for women and withdrawal-relevant negative affect for men whereas alleviating side effects may help smokers with elevated depressed symptoms achieve the first smoking cessation milestone.
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影响因子：
5.9
作者：
Japuntich, Sandra J.;Piper, Megan E.;Leventhal, Adam M.;Bolt, Daniel M.;Baker, Timothy B.
通讯作者：
Baker, Timothy B.
影响因子：
5.9
作者：
S. Kenford;Stevens S. Smith;D. Wetter;D. Jorenby;M. Fiore;T. Baker
通讯作者：
S. Kenford;Stevens S. Smith;D. Wetter;D. Jorenby;M. Fiore;T. Baker
DOI：
10.1080/14622200307259
发表时间：
2003
期刊：
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
影响因子：
--
作者：
J. McCaffery;R. Niaura;G. Swan;D. Carmelli
通讯作者：
J. McCaffery;R. Niaura;G. Swan;D. Carmelli
戒烟失败前标志物的生态瞬时评估分析。
影响因子：
2.3
作者：
Yeh,VivianM;McCarthy,DanielleE;Baker,TimothyB
通讯作者：
Baker,TimothyB
安非他酮和抑郁症认知行为治疗对戒烟治疗期间积极情感、消极情感和吸烟冲动的影响。
DOI：
10.1093/ntr/ntp111
发表时间：
2009
期刊：
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
影响因子：
--
作者：
Strong,DavidR;Kahler,ChristopherW;Leventhal,AdamM;Abrantes,AnaM;Lloyd-Richardson,Elizabeth;Niaura,Raymond;Brown,RichardA
通讯作者：
Brown,RichardA