Cardiac cryolesions: factors affecting their size and a means of monitoring their formation.

Cardiac cryolesions: factors affecting their size and a means of monitoring their formation.
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心脏冷冻损伤:影响其大小的因素以及监测其形成的方法。

DOI:
10.1016/s0003-4975(10)64691-7
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发表时间:
1988
期刊:
The Annals of thoracic surgery
影响因子:
--
通讯作者:
Hargrove3rd,WC
Hargrove3rd,WC
中科院分区:
--
文献类型:
--
作者:
Markovitz,LJ;Frame,LH;Josephson,ME;Hargrove3rd,WC

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对27只杂种犬的心内膜冷冻进行了分析,以确定初始心肌温度(37°C对12°C)和一氧化二氮输送管道内的压力(储罐压力大于700磅/平方英寸,储罐压力小于700磅/平方英寸)对冷冻大小的影响。此外,监测局部心肌温度以确定术中低温细胞死亡的程度。冷冻体积明显受初始心肌温度(p>0.001)和线压力(p=0.014)的影响。在37℃的心肌中,线压低于700psi时的平均损伤体积为0.501±0.183 cc,线压大于700psi时的平均损伤体积为0.839±0.258 cc。在12℃的心肌中,线压低于700psi时的平均体积为1.151±0.436 cc,高于700psi时的平均体积为1.361±0.288 cc,在细胞死亡区域的边缘出现0℃的心肌温度。当分析−5°C到+5°C的范围时,0°C或更低的点落入低温的概率为84.2%。监测心肌内温度将预测出血的边界。
Twenty-seven endocardial cryolesions were created in mongrel dogs and analyzed to determine the effects on cryolesion size of both the initial myocardial temperature (37°C versus 12°C) and the pressure within the nitrous oxide delivery line (tank pressure of more than 700 pounds per square inch [psi] versus tank pressure of less than 700 psi). In addition, local myocardial temperatures were monitored to determine their utility in the intraoperative determination of the extent of cryothermic cell death.Cryolesion volume was significantly affected by both the initial myocardial temperature (p> 0.001) and the line pressure (p= 0.014). In a 37°C myocardium, the mean lesion volume ranged from 0.501 ± 0.183 cc at line pressures lower than 700 psi to 0.839 ± 0.258 cc at line pressures greater than 700 psi. In a 12°C myocardium, the mean volume was 1.151 ± 0.436 cc at line pressures lower than 700 psi and 1.361 ± 0.288 cc at line pressures higher than 700 psi.A myocardial temperature of 0°C occurs at the edge of the area of cell death. When analyzing the range from −5° to +5°C, the probability of a point at or lower than 0°C falling inside the cryolesion is 84.2%. Monitoring intra-myocardial temperature will predict the border of a cryolesion.
DOI: 10.1161/01.cir.57.1.190
发表时间: 1978-01-01
期刊: CIRCULATION
影响因子: 37.8
作者:
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心室冷冻手术:对壁内电生理学的短期影响。
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发表时间: 1983
期刊: The Annals of thoracic surgery
影响因子: --
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期刊: The American journal of pathology
影响因子: --
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发表时间: 1979-01-01
期刊: CIRCULATION
影响因子: 37.8
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KLEIN, GJ;HARRISON, L;GALLAGHER, JJ
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