Healthy Intestinal Function Relies on Coordinated Enteric Nervous System, Immune System, and Epithelium Responses.

Healthy Intestinal Function Relies on Coordinated Enteric Nervous System, Immune System, and Epithelium Responses.
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DOI:
10.1080/19490976.2021.1916376
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发表时间:
2021-01
期刊:
影响因子:
12.2
通讯作者:
Diehl GE
Diehl GE
中科院分区:
医学2区
文献类型:
--
作者:
Saldana-Morales FB;Kim DV;Tsai MT;Diehl GE

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在健康和疾病期间,上皮细胞、免疫系统和肠神经系统之间的协调反应是适当的肠功能所必需的。虽然每个系统都对一些常见的刺激做出反应,但它们的协调反应支持消化以及损伤或病原体感染后的反应和恢复。在这篇综述中,我们讨论了如何共同信号的个人反应一起工作,以支持这些关键功能。
During both health and disease, a coordinated response between the epithelium, immune system, and enteric nervous system is required for proper intestinal function. While each system responds to a number of common stimuli, their coordinated responses support digestion as well as responses and recovery following injury or pathogenic infections. In this review, we discuss how individual responses to common signals work together to support these critical functions.
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