Spectral pattern of urinary water as a biomarker of estrus in the giant panda.
Spectral pattern of urinary water as a biomarker of estrus in the giant panda.
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DOI：
10.1038/srep00856
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发表时间：
2012
影响因子：
4.6
通讯作者：
Tsenkova, Roumiana
中科院分区：
文献类型：
--
作者：
Kinoshita, Kodzue;Miyazaki, Mari;Morita, Hiroyuki;Vassileva, Maria;Tang, Chunxiang;Li, Desheng;Ishikawa, Osamu;Kusunoki, Hiroshi;Tsenkova, Roumiana
近红外光谱(NIRS)已被成功地用于疾病和异常的非侵入性诊断，其中水的光谱模式起着重要的作用。本研究调查了雌性大熊猫发情期的吸水模式。尿样的近红外光谱是在连续三个假定发情期内每天从同一动物身上获得的。在12个特定吸水带的基础上发现了特征吸水率模式，表现出较高的尿谱变化，表明随着发情期的增加，氢键水结构增加。尿谱和雌酮-3-葡萄糖醛酸苷在这些水带的标准浓度的回归分析表明，与雌激素水平高度相关。尿谱的聚类分析将不同年份的发情样本分组在一起。这些结果为利用水结构作为分子镜快速检测发情开辟了新的途径。
Near infrared spectroscopy (NIRS) has been successfully used for non-invasive diagnosis of diseases and abnormalities where water spectral patterns are found to play an important role. The present study investigates water absorbance patterns indicative of estrus in the female giant panda. NIR spectra of urine samples were acquired from the same animal on a daily basis over three consecutive putative estrus periods. Characteristic water absorbance patterns based on 12 specific water absorbance bands were discovered, which displayed high urine spectral variation, suggesting that hydrogen-bonded water structures increase with estrus. Regression analysis of urine spectra and spectra of estrone-3-glucuronide standard concentrations at these water bands showed high correlation with estrogen levels. Cluster analysis of urine spectra grouped together estrus samples from different years. These results open a new avenue for using water structure as a molecular mirror for fast estrus detection.
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影响因子：
56.9
作者：
Shin, JW;Hammer, NI;Jordan, KD
通讯作者：
Jordan, KD
影响因子：
3.1
作者：
Kinoshita, Kodzue;Morita, Hiroyuki;Tsenkova, Roumiana
通讯作者：
Tsenkova, Roumiana
影响因子：
1.3
作者：
MASUI, M;HIRAMATSU, H;SAITO, K
通讯作者：
SAITO, K
DOI：
10.1016/s0731-7085(03)00345-5
发表时间：
2003-09-19
影响因子：
3.4
作者：
Fountain, W;Dumstorf, K;Mumper, RJ
通讯作者：
Mumper, RJ
DOI：
10.1016/j.saa.2004.03.016
发表时间：
2005-01-01
影响因子：
4.4
作者：
Medina-Gutiérrez, C;Quintanar, JL;Sato-Berrú, R
通讯作者：
Sato-Berrú, R