Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight.
Hydrogen therapy may reduce the risks related to radiation-induced oxidative stress in space flight.
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DOI：
10.1016/j.mehy.2010.08.046
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发表时间：
2011-01
影响因子：
4.7
通讯作者：
Nakao A
中科院分区：
文献类型：
--
作者：
Schoenfeld MP;Ansari RR;Zakrajsek JF;Billiar TR;Toyoda Y;Wink DA;Nakao A
已知宇宙辐射会引起与氧化应激增加相关的DNA和脂质损伤，并且仍然是太空旅行中的主要问题。氢气是近年来发现的一种新型医用气体，具有很强的抗氧化和抗炎作用。预计今后几年空间使命活动的数量和持续时间都将增加。因此，必须在出现疾病的临床症状之前估计和预防宇航员因氧化应激而遇到的风险。我们假设，通过吸入或饮用富氢水向宇航员提供氢可能会产生一种新的可行的预防/治疗策略，以防止辐射引起的不良事件。
Cosmic radiation is known to induce DNA and lipid damage associated with increased oxidative stress and remains a major concern in space travel. Hydrogen, recently discovered as a novel therapeutic medical gas in a variety of biomedical fields, has potent antioxidant and anti-inflammatory activities. It is expected that space mission activities will increase in coming years both in numbers and duration. It is therefore important to estimate and prevent the risks encountered by astronauts due to oxidative stress prior to developing clinical symptoms of disease. We hypothesize that hydrogen administration to the astronauts by either inhalation or drinking hydrogen-rich water may potentially yield a novel and feasible preventative/therapeutic strategy to prevent radiation-induced adverse events.
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影响因子：
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