Associations between simultaneous alcohol and cannabis use and next-day negative affect among young adults: The role of sex and trait anxiety.
Associations between simultaneous alcohol and cannabis use and next-day negative affect among young adults: The role of sex and trait anxiety.
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DOI：
10.1016/j.addbeh.2021.107082
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发表时间：
2021-12
影响因子：
4.4
通讯作者：
Lanza ST
中科院分区：
文献类型：
--
作者：
Linden-Carmichael AN;Hochgraf AK;Cloutier RM;Stull SW;Lanza ST
同时使用酒精和大麻（“同时使用酒精和大麻[SAM]”）在年轻人中很常见，并与负面物质相关的后果有关。SAM的使用可能与波动的情绪状态有关，如负面影响和个人特征，包括焦虑和性别的特征水平。然而，人们对他们的集体作用知之甚少。在这项研究中，我们试图了解SAM使用和负面影响之间的日常联系，以及这种联系是否会因特质焦虑和性别而不同。参与者是154名年轻人（57.8%女性，72.7%白色，M年龄= 20.2），他们完成了特质焦虑症状的基线调查和长达14个连续的日常调查，对他们的物质使用和情感状态。多水平模型测试了物质使用日类型（即，仅含酒精天数、仅含大麻天数和相对于SAM使用天数的不使用天数），第二天产生负面影响。三向和低阶的相互作用进行了测试，物质使用日类型，焦虑和性别。仅使用大麻的日子，焦虑和性之间以及仅使用酒精的日子，焦虑和性之间出现了两种三向相互作用，因此SAM的使用与第二天相对于单一物质使用日的负面影响相关，特别是在焦虑升高的女性参与者中。焦虑和性别是SAM使用相对于单一物质使用和日常负面影响之间联系的突出因素。研究结果强调了考虑所有这些因素的必要性，以便制定最有效的药物使用干预措施。
The simultaneous use of alcohol and cannabis (“simultaneous alcohol and marijuana [SAM] use”) is common among young adults and associated with negative substance-related consequences. SAM use may be tied to fluctuating mood states such as negative affect and individual characteristics including trait level of anxiety and sex. However, little is understood about their collective role. In this study, we sought to understand the daily link between SAM use and negative affect and whether this link might differ by both trait anxiety and sex. Participants were 154 young adults (57.8% female, 72.7% White, M age = 20.2) who completed baseline surveys on trait anxiety symptoms and up to 14 consecutive daily surveys on their substance use and affective states. Multilevel models tested for associations of type of substance use day (i.e., alcohol-only days, cannabis-only days, and no use days relative to SAM use days) with next-day negative affect. Three-way and lower order interactions were tested for substance use day type, anxiety, and sex. Two three-way interactions between cannabis-only days, anxiety, and sex and between alcohol-only days, anxiety, and sex emerged such that SAM use was associated with greater next-day negative affect relative to single substance use days particularly among female participants with elevated anxiety. Anxiety and sex are salient factors in the link between SAM use relative to single-substance use and daily negative affect. Study findings reinforce the need to account for all of these factors in order to develop maximally efficacious substance use interventions.
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