Time-Limited Eating and Continuous Glucose Monitoring in Adolescents with Obesity: A Pilot Study.

Time-Limited Eating and Continuous Glucose Monitoring in Adolescents with Obesity: A Pilot Study.
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DOI:
10.3390/nu13113697
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发表时间:
2021-10-21
期刊:
影响因子:
5.9
通讯作者:
Goran MI
Goran MI
中科院分区:
医学2区
文献类型:
--
作者:
Vidmar AP;Naguib M;Raymond JK;Salvy SJ;Hegedus E;Wee CP;Goran MI

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由于其简单性,与其他热量限制方案相比,与其他热量的饮食相比,肥胖症的青少年可能是一种更可行的方法。每天CM,并随机:(1)长时间的饮食窗口:12 h禁食 +盲人CGM(2)饮食(每周5天,饮食5天)探索为次要结果。四十五名参与者完成了研究(16.4±1.3岁,女性,有49%的西班牙裔,75%的公共保险)。据报道,限制他们的饮食窗口并佩戴CGM是可行的没有对每日功能或不良事件的负面影响。
Due to its simplicity, time-limited eating (TLE) may represent a more feasible approach for treating adolescents with obesity compared to other caloric restriction regimens. This pilot study examines the feasibility and safety of TLE combined with continuous glucose monitoring (CGM) in adolescents. Fifty adolescents with BMI ≥95th percentile were recruited to complete a 12-week study. All received standard nutritional counseling, wore a CGM daily, and were randomized to: (1) Prolonged eating window: 12 h eating/12 h fasting + blinded CGM; (2) TLE (8 h eating/16 h fasting, 5 days per week) + blinded CGM; (3) TLE + real-time CGM feedback. Recruitment, retention, and adherence were recorded as indicators of feasibility. Weight loss, dietary intake, physical activity, eating behaviors, and quality of life over the course of the intervention were explored as secondary outcomes. Forty-five participants completed the study (16.4 ± 1.3 years, 64% female, 49% Hispanic, 75% public insurance). There was high adherence to prescribed eating windows (TLE 5.2 d/wk [SD 1.1]; control 6.1 d/wk [SD 1.4]) and daily CGM wear (5.85 d/wk [SD 4.8]). Most of the adolescents (90%) assigned to TLE reported that limiting their eating window and wearing a CGM was feasible without negative impact on daily functioning or adverse events. There were no between-group difference in terms of weight loss, energy intake, quality of life, physical activity, or eating behaviors. TLE combined with CGM appears feasible and safe among adolescents with obesity. Further investigation in larger samples, with a longer intervention duration and follow-up assessments are needed.
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