Isolation and full-genome sequencing of Seneca Valley virus in piglets from China, 2016.
Isolation and full-genome sequencing of Seneca Valley virus in piglets from China, 2016.
复制标题
DOI：
10.1186/s12985-016-0631-2
复制
发表时间：
2016-10-19
期刊：
影响因子：
4.8
通讯作者：
Li X
中科院分区：
文献类型：
--
作者：
Qian S;Fan W;Qian P;Chen H;Li X
塞内卡谷病毒（Seneca valley virus，SVV）是一种与猪特发性水泡病（idiopathic vesicular disease，PIVD）相关的小型无包膜RNA病毒，属于小核糖核酸病毒科（Picornaviridae）成员。猪SVV感染可导致猪水疱病和流行性一过性新生儿丢失（ETNL）。2015年在中国南方广东报告了首例SVV感染病例。我们从中国中部湖北省患有PIVD的仔猪的水疱病变组织标本中分离并鉴定了SVV HB-CH-2016株。SVV HB-CH-2016株的全基因组序列与以往报道的SVV全基因组序列具有较高的核苷酸同源性（94%~ 99%），其中多聚蛋白的氨基酸序列同源性为98%~ 99%。因此，SVV HB-CH-2016毒株与SVV CH-01-2015毒株密切相关。本文报告的病例是我国第二例SVV感染病例。我们的研究结果表明，散发性SVV感染发生在中国中部，因此，积极监测猪群是重要的。此外，兽医必须重视这种水泡性疾病，加强生物安全措施，防止SVV传播。本文的在线版本（doi：10.1186/s12985-016-0631-2）包含补充材料，可供授权用户使用。
Seneca valley virus (SVV), a member of the Picornaviridae family, is a small non-enveloped RNA virus, that is linked to porcine idiopathic vesicular disease (PIVD). SVV infection in swine results in vesicular disease and epidemic transient neonatal losses (ETNL). The first case of SVV infection was reported in Guangdong, South China in 2015. We isolated and characterized an SVV HB-CH-2016 strain from vesicular lesion tissue specimens from piglets with PIVD in Hubei, Central China. The complete genome sequence of SVV HB-CH-2016 strain shares high nucleotide identities (94 to 99 %) with all previously reported SVV genomes, moreover, the polyprotein accounts for 98–99 % of amino acid sequence identity. Therefore, the SVV HB-CH-2016 strain is closely related to the SVV CH-01-2015 strain. The case reported in this paper is the second SVV infection case in China. Our findings demonstrate that sporadic SVV infection has occurred in Central China, and therefore, active surveillance on the swine population is important. Moreover, veterinarians must pay attention to this vesicular disease and reinforce biosecurity measures and prevent SVV spread. The online version of this article (doi:10.1186/s12985-016-0631-2) contains supplementary material, which is available to authorized users.
登录
查看更多内容
影响因子：
9.4
作者：
Gimenez-Lirola, Luis Gabriel;Rademacher, Chris;Pineyro, Pablo
通讯作者：
Pineyro, Pablo
影响因子：
4.3
作者：
Vannucci, F. A.;Linhares, D. C. L.;Marthaler, D.
通讯作者：
Marthaler, D.
影响因子：
11.8
作者：
Montiel N;Buckley A;Guo B;Kulshreshtha V;VanGeelen A;Hoang H;Rademacher C;Yoon KJ;Lager K
通讯作者：
Lager K
影响因子：
7.6
作者：
Fan, Wenchun;Zhang, Dong;Li, Xiangmin
通讯作者：
Li, Xiangmin
影响因子：
4.3
作者：
Canning, P.;Canon, A.;Karriker, L.
通讯作者：
Karriker, L.