Examination of premenstrual symptoms as a risk factor for depression in postpartum women.
Examination of premenstrual symptoms as a risk factor for depression in postpartum women.
复制标题
DOI：
10.1007/s00737-012-0323-x
复制
发表时间：
2013-06
影响因子：
4.5
通讯作者：
O'Hara, Michael W.
中科院分区：
文献类型：
--
作者：
Buttner, Melissa M.;Mott, Sarah L.;Pearlstein, Teri;Stuart, Scott;Zlotnick, Caron;O'Hara, Michael W.
关键词：
产后抑郁症（PPD）是一个重要的公共卫生问题，在产后的前三个月，重度和轻度抑郁症的患病率达到20%。PPD的社会人口统计学和精神病理学相关性已经得到了很好的建立，但是，经前疾病和PPD发展之间关系的信息还不太明确。因此，本研究的目的是探讨经前综合征（PMS）/经前焦虑障碍（PMDD）作为PPD危险因素的作用。采用经前症状筛查工具（PSST）对经前症状进行回顾性评估，根据DSM-IV标准诊断抑郁症，并采用HDRS进行评估。采用两阶段筛选程序。在第一阶段，使用PHQ-9。在第二阶段，对PHQ-9上确认≥ 5种症状的女性进行SCID、HDRS和PSST。分层线性回归显示，抑郁症史和PMS/PMDD贡献了额外的2%的方差（p <0.001），超出了社会人口因素的影响。完整的模型解释了产后抑郁症状的13%的方差。Logistic回归分析显示，经前综合征/经前抑郁症与产后抑郁症之间也存在显著相关性（OR=1.97）。本研究的结果表明，PMS/PMDD是PPD的一个重要的危险因素。有PMS/PMDD病史的妇女应在围产期进行监测。
Postpartum depression (PPD) is a significant public health concern with prevalence of major and minor depression reaching 20% in the first three postpartum months. Sociodemographic and psychopathology correlates of PPD are well-established; however, information on the relationship between premenstrual disorders and the development of PPD is less well-established. Thus, the aim of this study was to examine the role of premenstrual syndrome (PMS)/premenstrual dysphoric disorder (PMDD) as a risk factor for PPD. Premenstrual symptoms were assessed retrospectively using the Premenstrual Symptoms Screening Tool (PSST) and depression was diagnosed according to DSM-IV criteria and assessed using the HDRS. A two-stage screening procedure was applied. In the first stage, the PHQ-9 was employed. In the second stage, women endorsing ≥ 5 symptoms on the PHQ-9 were administered the SCID, HDRS, and PSST. Hierarchical linear regression showed that history of depression and PMS/PMDD contributed an additional 2% of the variance (p < .001), beyond that of sociodemographic factor effects. The full model accounted for 13% of the variance in postpartum depressive symptoms. Using logistic regression, a significant association also emerged between PMS/PMDD and PPD (OR=1.97). The findings of this study suggest that PMS/PMDD is an important risk factor for PPD. Women endorsing a history of PMS/PMDD should be monitored during the perinatal period.
登录
查看更多内容
影响因子：
6.7
作者：
Moses-Kolko, Eydie L.;Wisner, Katherine L.;Meltzer, Carolyn C.
通讯作者：
Meltzer, Carolyn C.
影响因子：
--
作者：
O'Hara, MW;Stuart, S;Wenzel, A
通讯作者：
Wenzel, A
影响因子：
0.5
作者：
Kroenke, K;Spitzer, RL
通讯作者：
Spitzer, RL
影响因子：
3.7
作者：
Halbreich, U;Borenstein, J;Kahn, LS
通讯作者：
Kahn, LS
影响因子：
2.3
作者：
Jovanovic, Hristina;Cerin, Asta;Nordstrom, Anna-Lena
通讯作者：
Nordstrom, Anna-Lena