Reassortment of pandemic H1N1/2009 influenza A virus in swine.

Reassortment of pandemic H1N1/2009 influenza A virus in swine.
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DOI:
10.1126/science.1189132
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发表时间:
2010-06-18
期刊:
Science (New York, N.Y.)
影响因子:
--
通讯作者:
Guan Y
Guan Y
中科院分区:
其他
文献类型:
--
作者:
Vijaykrishna D;Poon LL;Zhu HC;Ma SK;Li OT;Cheung CL;Smith GJ;Peiris JS;Guan Y

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H1N1/2009流感大流行的出现表明大流行病毒可以在猪体内产生。随后,H1N1/2009病毒再次传入猪群的情况已在多个国家发生。通过对来自香港屠宰场的猪流感病毒的系统监测,我们描述了H1N1/2009与猪病毒的重组后代。H1N1/2009与猪流感病毒的持续重组可能产生具有传播性和对人类毒力改变的变体。有必要对猪流感病毒进行全球系统监测。
The emergence of pandemic H1N1/2009 influenza demonstrated that pandemic viruses could be generated in swine. Subsequent re-introduction of H1N1/2009 to swine has occurred in multiple countries. Through systematic surveillance of influenza viruses in swine from a Hong Kong abattoir, we characterize a reassortant progeny of H1N1/2009 with swine viruses. Continued reassortment of H1N1/2009 with swine influenza viruses could produce variants with transmissibility and altered virulence for humans. Global systematic surveillance of influenza viruses in swine is warranted.
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影响因子: 6.4
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