The treatment effect of porous titanium alloy rod on the early stage talar osteonecrosis of sheep.
The treatment effect of porous titanium alloy rod on the early stage talar osteonecrosis of sheep.
复制标题
多孔钛合金棒治疗羊早期距骨骨坏死的效果
DOI：
10.1371/journal.pone.0058459
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
Guo Z
中科院分区：
文献类型：
--
作者：
Li XK;Yuan CF;Wang JL;Zhang YQ;Zhang ZY;Guo Z
距骨骨坏死（ONT）可能会严重影响踝关节的功能。大多数骨科医生认为ONT应该早期治疗，但缺乏简洁有效的手术治疗方法。本研究制备多孔钛合金棒并植入早期ONT绵羊足底（IM组）。将棒的疗效与核心减压治疗（DC组）进行比较。干预后1个月，两组骨重建情况无显着差异。 3个月后，IM组大体标本肉眼观察轮廓正常，而DC组标本出现明显的部分骨缺损和软骨退变。通过显微CT和组织学研究对重建的小梁进行定量分析表明，干预后3个月IM组的疗效优于DC组。将多孔钛合金棒植入患有早期 ONT 的绵羊足底中的这些有利的短期结果可能为 ONT 的创新手术治疗提供见解。
Osteonecrosis of the talus (ONT) may severely affect the function of the ankle joint. Most orthopedists believe that ONT should be treated at an early stage, but a concise and effective surgical treatment is lacking. In this study, porous titanium alloy rods were prepared and implanted into the tali of sheep with early-stage ONT (IM group). The curative effect of the rods was compared to treatment by core decompression (DC group). No significant differences in bone reconstruction were observed between the two groups at 1 month after intervention. After 3 months, the macroscopic view of gross specimens of the IM group showed ordinary contours, but the specimens of the DC group showed obvious partial bone defects and cartilage degeneration. Quantitative analysis of the reconstructed trabeculae by micro-CT and histological study suggested that the curative effect of the IM group was superior to that of the DC group at 3 months after intervention. These favorable short-term results of the implantation of porous titanium alloy rods into the tali of sheep with early-stage ONT may provide insight into an innovative surgical treatment for ONT.
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影响因子：
2.6
作者：
Petcu EB;Ivanovski S;Wright RG;Slevin M;Miroiu RI;Brinzaniuc K
通讯作者：
Brinzaniuc K
影响因子：
2.4
作者：
Manggold, J;Sergi, C;Simank, HG
通讯作者：
Simank, HG
影响因子：
2.7
作者：
Floerkemeier, Thilo;Thorey, Fritz;von Lewinski, Gabriela
通讯作者：
von Lewinski, Gabriela
微波加热组织工程骨修复新型股骨头坏死动物模型
影响因子：
2.7
作者：
Li, Yanlin;Han, Rui;Wei, Lei
通讯作者：
Wei, Lei
DOI：
10.2106/00004623-199804000-00009
发表时间：
1998-04-01
影响因子：
5.3
作者：
Delanois, RE;Mont, MA;Hungerford, DS
通讯作者：
Hungerford, DS