Direct Electrospray Ionization Mass Spectrometric Profiling of Real-World Samples via a Solid Sampling Probe
Direct Electrospray Ionization Mass Spectrometric Profiling of Real-World Samples via a Solid Sampling Probe
复制标题
通过固体采样探针对真实样品进行直接电喷雾电离质谱分析
DOI:
10.1007/s13361-013-0697-7
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发表时间:
2013-07
影响因子:
3.2
通讯作者:
于湛
中科院分区:
文献类型:
--
作者:
于湛
This study presents a novel direct analysis strategy for rapid mass spectrometric profiling of biochemicals in real-world samples via a direct sampling probe (DSP) without sample pretreatments. Chemical modification is applied to a disposable stainless steel acupuncture needle to enhance its surface area and hydrophilicity. After insertion into real-world samples, biofluid can be attached on the DSP surface. With the presence of a high DC voltage and solvent vapor condensing on the tip of the DSP, analyte can be dissolved and electrosprayed. The simplicity in design, versatility in application aspects, and other advantages such as low cost and disposability make this new method a competitive tool for direct analysis of real-world samples.
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影响因子:
2
作者:
Shiea, J;Huang, MZ;Sunner, J
通讯作者:
Sunner, J
影响因子:
4.2
作者:
Hu, Bin;Lai, Ying-Han;Yao, Zhong-Ping
通讯作者:
Yao, Zhong-Ping
DOI:
10.1088/0960-1317/23/6/065009
发表时间:
2013-06-01
影响因子:
2.3
作者:
Acero, A. J.;Rebollo-Munoz, N.;Vega, E. J.
通讯作者:
Vega, E. J.
DOI:
10.1016/j.colsurfa.2006.03.008
发表时间:
2006-09-01
影响因子:
5.2
作者:
Stalder, A. F.;Kulik, G.;Hoffmann, P.
通讯作者:
Hoffmann, P.
影响因子:
4.2
作者:
Rezenom, Yohannes H.;Dong, Jianan;Murray, Kermit K.
通讯作者:
Murray, Kermit K.