Design, synthesis, and characterization of nucleic-acid-functionalized gold surfaces for biomarker detection.
Design, synthesis, and characterization of nucleic-acid-functionalized gold surfaces for biomarker detection.
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DOI：
10.1021/la2028862
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发表时间：
2012-01-17
期刊：
影响因子：
--
通讯作者：
Wright DW
中科院分区：
文献类型：
--
作者：
Adams NM;Jackson SR;Haselton FR;Wright DW
Nucleic acid-functionalized gold surfaces have been used extensively for the development of biological sensors. The development of an effective biomarker detection assay requires careful design, synthesis and characterization of probe components. In this feature article, we describe fundamental probe development constraints and provide a critical appraisal of the current methodologies and applications in the field. We discuss critical issues and obstacles that impede the sensitivity and reliability of the sensors to underscore the challenges that must be met to advance the field of biomarker detection.
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影响因子：
4.7
作者：
Gorodetsky, Alon A.;Buzzeo, Marisa C.;Barton, Jacqueline K.
通讯作者：
Barton, Jacqueline K.
影响因子：
15
作者：
Jayagopal, Ashwath;Halfpenny, Kristin C.;Perez, Jonas W.;Wright, David W.
通讯作者：
Wright, David W.
影响因子：
6.1
作者：
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通讯作者：
Liu, Chang
DOI：
10.1007/bf01498565
发表时间：
1972-01-01
期刊：
KOLLOID-ZEITSCHRIFT AND ZEITSCHRIFT FUR POLYMERE
影响因子：
--
作者：
FRENS, G
通讯作者：
FRENS, G
影响因子：
46.9
作者：
Dubertret, B;Calame, M;Libchaber, AJ
通讯作者：
Libchaber, AJ