Effect of moxibustion on long-term memory in vascular dementia model rats
Effect of moxibustion on long-term memory in vascular dementia model rats
复制标题
艾灸对血管性痴呆模型大鼠长期记忆的影响
DOI：
10.1016/j.wjam.2019.04.008
复制
发表时间：
2019-03
影响因子：
0.7
通讯作者：
Fan Yinqiu
中科院分区：
文献类型：
--
作者：
Li Yue;Yang Jun;Gui Li;Fan Yinqiu
Objective: To observe the effects on spatial long-term memory in the rats with vascular dementia (VD) treated with moxibustion for resolving stasis and promoting meridian circulation. Methods: The modified 2-vascular occlusion (2-VO) method was used to prepare VD animal model. The rats were randomized into a sham-operation group, a model group, a moxibustion group and a western medication group, 15 rats in each one. In the moxibustion group, mild warm moxibustion was applied to “Baihui (百会 GV 20)” “Dazhui (大椎GV 14)” and “Shenting (神庭GV 24)”, 20 min at each point, once a day, for 3 weeks consecutively. In the western medicaion group, mouse nerve growth factor (NGF) was injected intraperitoneally, 0.18 mL/kg, once a day, for 3 weeks consecutively. Morris water maze test was used, the time of the first passing platform, the frequency of passing-platform and swimming speed in 120 s were determined of the rats in each group. Western blot were used to test the protein expressions of hippocampal Nestin and DCX. Results: At the end of three courses of treatment, compared with sham-operation group, the difference was not significant statistically in swimming speed in the model group, the moxibustion group and the western medication group separately (all P > 0.05). Three days after modeling, the mean of escape latency was prolonged obviously in the modeled rats compared with the rats in the shamoperation group (88.84 ±19.94 vs 18.15 ±9.41, P 0.05).
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DOI：
--
发表时间：
2013
期刊：
Chinese Journal of Stroke
影响因子：
--
作者：
Q. Yan
通讯作者：
Q. Yan
DOI：
--
发表时间：
2015
期刊：
Journal of Clinical Acupuncture and Moxibustion
影响因子：
--
作者：
Wang Ming-ji
通讯作者：
Wang Ming-ji
DOI：
--
发表时间：
2014-04
期刊：
Zhen ci yan jiu = Acupuncture research
影响因子：
--
作者：
Hui-zhen Zhang;Yu-lei Liang;Xue-jing Zhang;Chuang Zhang;Yan-hui Sun;Xiufeng Zhang;Xiao-kang Xu;Rui-Guo Jia;Xin-Guo Wang
通讯作者：
Hui-zhen Zhang;Yu-lei Liang;Xue-jing Zhang;Chuang Zhang;Yan-hui Sun;Xiufeng Zhang;Xiao-kang Xu;Rui-Guo Jia;Xin-Guo Wang
DOI：
10.1007/978-3-030-22009-9_719
发表时间：
2021
期刊：
Encyclopedia of Gerontology and Population Aging
影响因子：
--
作者：
Margaret Wiggins;C. Price
通讯作者：
Margaret Wiggins;C. Price
影响因子：
4.6
作者：
Gehring TV;Luksys G;Sandi C;Vasilaki E
通讯作者：
Vasilaki E