A social affective neuroscience lens on placebo analgesia.

A social affective neuroscience lens on placebo analgesia.
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DOI:
10.1016/j.tics.2021.07.016
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发表时间:
2021-11
影响因子:
19.9
通讯作者:
Atlas LY
Atlas LY
中科院分区:
心理学1区
文献类型:
--
作者:
Atlas LY

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疼痛是促进生存的基本经验。在人类中,疼痛处于多种健康危机的交叉点:慢性疼痛,阿片类药物流行病和健康差异。安慰剂镇痛的研究强调了社会,认知和情感过程如何直接塑造疼痛,并确定了缓解这些危机的潜在途径。在这篇综述中,我检查了最近的进展,安慰剂镇痛的研究,通过情感科学。我专注于安慰剂效应是如何通过期望,影响和治疗周围的社会背景形成的,并讨论安慰剂的神经生物学机制,突出未回答的问题和对健康的影响。临床医生与社会和情感科学家之间的合作可以解决悬而未决的问题,并利用安慰剂来减轻疼痛和改善人类健康。
Pain is a fundamental experience that promotes survival. In humans, pain stands at the intersection of multiple health crises: chronic pain, the opioid epidemic, and health disparities. The study of placebo analgesia highlights how social, cognitive, and affective processes can directly shape pain and identifies potential paths for mitigating these crises. In this review, I examine recent progress in the study of placebo analgesia through affective science. I focus on how placebo effects are shaped by expectations, affect, and the social context surrounding treatment, and discuss neurobiological mechanisms of placebo, highlighting unanswered questions and implications for health. Collaborations between clinicians and social and affective scientists can address outstanding questions and leverage placebo to reduce pain and improve human health.
DOI: 10.1038/nrn3950
发表时间: 2015-07
期刊: Nature reviews. Neuroscience
影响因子: --
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