Bullous pemphigoid and ulcerative colitis.

Bullous pemphigoid and ulcerative colitis.
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大疱性类天疱疮和溃疡性结肠炎。

DOI:
10.1111/j.1365-4362.1982.tb02042.x
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发表时间:
1982
影响因子:
3.6
通讯作者:
Pitt,H
Pitt,H
中科院分区:
医学4区
文献类型:
--
作者:
Ahmed,AR;Kaplan,RP;Hardy,D;Feldman,E;Pitt,H

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一名患有溃疡性结肠炎14年的21岁白色女性,发生全身性重度大疱性类天疱疮。结肠切除后,她的皮肤显示出明显的临床改善,但这只是暂时的。对手术标本进行直接免疫荧光,没有明显的结肠粘膜细胞抗体(BMZ)。在直接和间接免疫荧光研究中发现抗基底膜带抗体,并且持续存在。来自15名溃疡性结肠炎患者和11名克罗恩病患者的血清,评价抗基底膜带抗体的存在,不含任何可证实水平的抗BMZ抗体。溃疡性结肠炎和大疱性类天疱疮的共存更可能是偶然的,而不是病因。
A 21‐year‐old white woman, who had ulcerative colitis for 14 years, developed generalized severe bullous pemphigoid. Following the resection of her colon, her skin showed marked clinical improvement, but this was only temporary. Direct immunofluorescence was performed on the surgical specimen and no antibodies (BMZ) to colonic mucosal cells were evident. Anti‐basement membrane zone antibodies were found on direct and indirect immunofluorescent studies and have persisted. Sera from 15 patients with ulcerative colitis and 11 patients with Crohn's disease, evaluated for the presence of an anti‐basement membrane zone antibody did not contain any demonstrable levels of anti‐BMZ antibodies. The co‐existence of ulcerative colitis and bullous pemphigoid is more likely incidental rather than etiopathologic.
精氨酸特异性试剂消除钠通道失活
DOI: 10.1038/271473a0
发表时间: 1978
期刊: Nature
影响因子: 64.8
作者:
D. Eaton;M. Brodwick;G. Oxford;B. Rudy
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发表时间: 1988
影响因子: 4.8
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钙通道:选择性、渗透和阻断机制。
DOI: --
发表时间: 1987
期刊: Annual Review of Biophysics and Biophysical Chemistry
影响因子: --
作者:
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通讯作者: R. Rosenberg
DOI: --
发表时间: 1982
期刊: Blood
影响因子: 20.3
作者:
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